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Association of Transfer RNA Fragments in White Blood Cells With Antibody Response to Bovine Leukemia Virus in Holstein Cattle

Overview of attention for article published in Frontiers in Genetics, July 2018
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  • Above-average Attention Score compared to outputs of the same age (60th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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Title
Association of Transfer RNA Fragments in White Blood Cells With Antibody Response to Bovine Leukemia Virus in Holstein Cattle
Published in
Frontiers in Genetics, July 2018
DOI 10.3389/fgene.2018.00236
Pubmed ID
Authors

Tasia M. Taxis, Marcus E. Kehrli, Rui D’Orey-Branco, Eduardo Casas

Abstract

Bovine leukemia virus (BLV) affects cattle health and productivity worldwide, causing abnormal immune function and immunosuppression. Transfer RNA fragments (tRFs) are known to be involved in inhibition of gene expression and have been associated with stress and immune response, tumor growth, and viral infection. The objective of this study was to identify tRFs associated with antibody response to BLV in Holstein cattle. Sera from 14 animals were collected to establish IgG reactivity to BLV by ELISA. Seven animals were seropositive (positive group) and seven were seronegative (negative group) for BLV exposure. Leukocytes from each animal were collected and tRFs were extracted for sequencing. tRF5GlnCTG, tRF5GlnTTG, and tRF5HisGTG, were significantly different between seropositive and seronegative groups (P < 0.0067). In all cases the positive group had a lower number of normalized sequences for tRFs when compared to the negative group. Result suggests that tRF5s could potentially be used as biomarkers to establish exposure of cattle to BLV.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 26%
Researcher 3 16%
Student > Ph. D. Student 2 11%
Student > Doctoral Student 2 11%
Student > Bachelor 1 5%
Other 1 5%
Unknown 5 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 26%
Veterinary Science and Veterinary Medicine 3 16%
Biochemistry, Genetics and Molecular Biology 3 16%
Medicine and Dentistry 2 11%
Business, Management and Accounting 1 5%
Other 2 11%
Unknown 3 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2023.
All research outputs
#7,646,969
of 23,565,002 outputs
Outputs from Frontiers in Genetics
#2,506
of 12,589 outputs
Outputs of similar age
#128,748
of 329,112 outputs
Outputs of similar age from Frontiers in Genetics
#50
of 140 outputs
Altmetric has tracked 23,565,002 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 12,589 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,112 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.