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mTOR Signaling, Translational Control, and the Circadian Clock

Overview of attention for article published in Frontiers in Genetics, September 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (60th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

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5 X users
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1 Facebook page
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1 Google+ user

Citations

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56 Dimensions

Readers on

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99 Mendeley
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Title
mTOR Signaling, Translational Control, and the Circadian Clock
Published in
Frontiers in Genetics, September 2018
DOI 10.3389/fgene.2018.00367
Pubmed ID
Authors

Ruifeng Cao

Abstract

Almost all cellular processes are regulated by the approximately 24 h rhythms that are endogenously driven by the circadian clock. mRNA translation, as the most energy consuming step in gene expression, is temporally controlled by circadian rhythms. Recent research has uncovered key mechanisms of translational control that are orchestrated by circadian rhythmicity and in turn feed back to the clock machinery to maintain robustness and accuracy of circadian timekeeping. Here I review recent progress in our understanding of translation control mechanisms in the circadian clock, focusing on a role for the mammalian/mechanistic target of rapamycin (mTOR) signaling pathway in modulating entrainment, synchronization and autonomous oscillation of circadian clocks. I also discuss the relevance of circadian mTOR functions in disease.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 99 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 18%
Student > Ph. D. Student 12 12%
Student > Master 9 9%
Student > Bachelor 9 9%
Professor > Associate Professor 4 4%
Other 11 11%
Unknown 36 36%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 23 23%
Agricultural and Biological Sciences 12 12%
Neuroscience 9 9%
Medicine and Dentistry 6 6%
Immunology and Microbiology 2 2%
Other 6 6%
Unknown 41 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2018.
All research outputs
#8,724,897
of 26,552,644 outputs
Outputs from Frontiers in Genetics
#2,768
of 14,013 outputs
Outputs of similar age
#137,000
of 351,721 outputs
Outputs of similar age from Frontiers in Genetics
#81
of 226 outputs
Altmetric has tracked 26,552,644 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 14,013 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,721 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.
We're also able to compare this research output to 226 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.