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Williams–Beuren Syndrome as a Potential Risk Factor for Burkitt Lymphoma

Overview of attention for article published in Frontiers in Genetics, September 2018
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Title
Williams–Beuren Syndrome as a Potential Risk Factor for Burkitt Lymphoma
Published in
Frontiers in Genetics, September 2018
DOI 10.3389/fgene.2018.00368
Pubmed ID
Authors

Ryo Kimura, Yuko Ishii, Kiyotaka Tomiwa, Tomonari Awaya, Masatoshi Nakata, Takeo Kato, Shin Okazaki, Toshio Heike, Masatoshi Hagiwara

Abstract

Williams-Beuren syndrome (WBS) is a multisystemic neurodevelopmental disorder caused by a hemizygous deletion on chromosome 7q11.23. Though at present there is a limited number of reports on WBS patients with tumors, most cases are related to blood cancer in children with WBS. We describe a case of Burkitt lymphoma in a 21-year-old man with WBS. In addition to providing a summary of published reports describing tumors observed in patients with WBS, we present a hypothesis about a possible mechanism of oncogenesis. In particular, we identified some significantly dysregulated cancer-related genes using blood samples from this patient at the age of 19 years (who have not yet developed Burkitt lymphoma). Our findings may provide a new perspective on the relation between WBS and Burkitt lymphoma.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 22%
Student > Ph. D. Student 3 17%
Student > Postgraduate 2 11%
Professor 2 11%
Other 1 6%
Other 2 11%
Unknown 4 22%
Readers by discipline Count As %
Medicine and Dentistry 8 44%
Biochemistry, Genetics and Molecular Biology 3 17%
Agricultural and Biological Sciences 1 6%
Psychology 1 6%
Immunology and Microbiology 1 6%
Other 0 0%
Unknown 4 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2018.
All research outputs
#15,544,609
of 23,102,082 outputs
Outputs from Frontiers in Genetics
#5,533
of 12,152 outputs
Outputs of similar age
#212,131
of 335,392 outputs
Outputs of similar age from Frontiers in Genetics
#124
of 205 outputs
Altmetric has tracked 23,102,082 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,152 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,392 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 205 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.