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The Role of the Innate Immune System in Granulomatous Disorders

Overview of attention for article published in Frontiers in immunology, January 2013
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92 Mendeley
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Title
The Role of the Innate Immune System in Granulomatous Disorders
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00120
Pubmed ID
Authors

Helen J. Petersen, Andrew M. Smith

Abstract

The dynamic structure of the granuloma serves to protect the body from microbiological challenge. This organized aggregate of immune cells seeks to contain this challenge and protect against dissemination, giving host immune cells a chance to eradicate the threat. A number of systemic diseases are characterized by this specialized inflammatory process and granulomas have been shown to develop at multiple body sites and in various tissues. Central to this process is the macrophage and the arms of the innate immune response. This review seeks to explore how the innate immune response drives this inflammatory process in a contrast of diseases, particularly those with a component of immunodeficiency. By understanding the genes and inflammatory mechanisms behind this specialized immune response, will guide research in the development of novel therapeutics to combat granulomatous diseases.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 1%
Unknown 91 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 20%
Student > Master 12 13%
Student > Bachelor 11 12%
Researcher 10 11%
Student > Doctoral Student 5 5%
Other 14 15%
Unknown 22 24%
Readers by discipline Count As %
Medicine and Dentistry 20 22%
Immunology and Microbiology 15 16%
Biochemistry, Genetics and Molecular Biology 13 14%
Agricultural and Biological Sciences 8 9%
Computer Science 2 2%
Other 7 8%
Unknown 27 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2013.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Frontiers in immunology
#22,563
of 31,507 outputs
Outputs of similar age
#221,301
of 288,986 outputs
Outputs of similar age from Frontiers in immunology
#240
of 503 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,507 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,986 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.