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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Immunosenescence and Novel Vaccination Strategies for the Elderly
|
|---|---|
| Published in |
Frontiers in immunology, January 2013
|
| DOI | 10.3389/fimmu.2013.00171 |
| Pubmed ID | |
| Authors |
Michael G. Dorrington, Dawn M. E. Bowdish |
| Abstract |
Vaccination remains the most effective prophylactic intervention for infectious disease in the healthcare professional's toolkit. However, the efficacy and effectiveness of vaccines decrease with age. This becomes most apparent after an individual reaches 65-70 years old, and results from complex changes in the immune system that occur during aging. As such, new vaccine formulations and strategies that can accommodate age-related changes in immunity are required to protect this expanding population. Here, we summarize the consequences of immunosenescence on vaccination and how novel vaccination strategies can be designed to accommodate the aging immune system. We conclude that current vaccination protocols are not sufficient to protect our aging population and, in some cases, are an inefficient use of healthcare resources. However, researchers and clinicians are developing novel vaccination strategies that include modifying who and when we vaccinate and capitalize on existing vaccines, in addition to formulating new vaccines specifically tailored to the elderly in order to remedy this deficiency. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 2 | 17% |
| United States | 2 | 17% |
| Singapore | 1 | 8% |
| Brazil | 1 | 8% |
| India | 1 | 8% |
| France | 1 | 8% |
| Canada | 1 | 8% |
| Unknown | 3 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 92% |
| Scientists | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 145 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Portugal | 1 | <1% |
| Canada | 1 | <1% |
| Taiwan | 1 | <1% |
| Mexico | 1 | <1% |
| Unknown | 139 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 16% |
| Student > Ph. D. Student | 22 | 15% |
| Student > Bachelor | 20 | 14% |
| Student > Master | 18 | 12% |
| Student > Postgraduate | 8 | 6% |
| Other | 23 | 16% |
| Unknown | 31 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 25% |
| Medicine and Dentistry | 26 | 18% |
| Immunology and Microbiology | 19 | 13% |
| Biochemistry, Genetics and Molecular Biology | 7 | 5% |
| Nursing and Health Professions | 6 | 4% |
| Other | 13 | 9% |
| Unknown | 38 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2020.
All research outputs
#1,838,661
of 25,728,855 outputs
Outputs from Frontiers in immunology
#1,702
of 32,269 outputs
Outputs of similar age
#16,433
of 290,908 outputs
Outputs of similar age from Frontiers in immunology
#16
of 503 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,269 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,908 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.