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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Functional Significance of CD57 Expression on Human NK Cells and Relevance to Disease
|
|---|---|
| Published in |
Frontiers in immunology, January 2013
|
| DOI | 10.3389/fimmu.2013.00422 |
| Pubmed ID | |
| Authors |
Carolyn M. Nielsen, Matthew J. White, Martin R. Goodier, Eleanor M. Riley |
| Abstract |
Historically, human NK cells have been identified as CD3(-)CD56(+)CD16(±) lymphocytes. More recently it has been established that CD57 expression defines functionally discrete sub-populations of NK cells. On T cells, CD57 expression has been regarded as a marker of terminal differentiation and (perhaps wrongly) of anergy and senescence. Similarly, CD57 expression seems to identify the final stages of peripheral NK cell maturation; its expression increases with age and is associated with chronic infections, particularly human cytomegalovirus infection. However, CD57(+) NK cells are highly cytotoxic and their presence seems to be beneficial in a number of non-communicable diseases. The purpose of this article is to review our current understanding of CD57 expression as a marker of NK cell function and disease prognosis, as well as to outline areas for further research. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 11% |
| Unknown | 8 | 89% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 67% |
| Scientists | 1 | 11% |
| Science communicators (journalists, bloggers, editors) | 1 | 11% |
| Practitioners (doctors, other healthcare professionals) | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 384 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | <1% |
| United Kingdom | 2 | <1% |
| Spain | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 377 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 73 | 19% |
| Student > Ph. D. Student | 67 | 17% |
| Student > Master | 44 | 11% |
| Student > Bachelor | 38 | 10% |
| Student > Doctoral Student | 28 | 7% |
| Other | 46 | 12% |
| Unknown | 88 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 78 | 20% |
| Immunology and Microbiology | 78 | 20% |
| Agricultural and Biological Sciences | 63 | 16% |
| Biochemistry, Genetics and Molecular Biology | 31 | 8% |
| Engineering | 6 | 2% |
| Other | 28 | 7% |
| Unknown | 100 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2023.
All research outputs
#7,377,389
of 26,311,549 outputs
Outputs from Frontiers in immunology
#8,223
of 32,936 outputs
Outputs of similar age
#71,140
of 294,444 outputs
Outputs of similar age from Frontiers in immunology
#86
of 503 outputs
Altmetric has tracked 26,311,549 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 32,936 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 294,444 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.