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Dendritic Cells in Cancer Immunotherapy Clinical Trials: Are We Making Progress?

Overview of attention for article published in Frontiers in immunology, January 2013
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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Citations

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Readers on

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132 Mendeley
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Title
Dendritic Cells in Cancer Immunotherapy Clinical Trials: Are We Making Progress?
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00454
Pubmed ID
Authors

Lisa H. Butterfield

Abstract

Dendritic cells (DC) have been tested in cancer immunotherapy clinical trials for two decades. Over this time, the methods of DC culture (or manufacture) have evolved, the approaches for antigen loading have broadened, the maturation signals have varied and different sites of administration have been tested. The post-vaccination immunologic questions asked have also varied between trials and over time. In this review, I will consider multiple aspects of DC-based vaccines tested in cancer patients, including the cell culture, antigen loading, maturation, and delivery, as well as what we have learned from testing immune responses in vaccinated patients who have benefited clinically, and those who have not measurably benefited.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Germany 1 <1%
Unknown 130 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 20%
Student > Master 22 17%
Researcher 21 16%
Student > Bachelor 12 9%
Other 12 9%
Other 21 16%
Unknown 18 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 36 27%
Immunology and Microbiology 24 18%
Medicine and Dentistry 19 14%
Biochemistry, Genetics and Molecular Biology 15 11%
Chemistry 7 5%
Other 9 7%
Unknown 22 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2013.
All research outputs
#16,722,190
of 25,374,917 outputs
Outputs from Frontiers in immunology
#18,325
of 31,520 outputs
Outputs of similar age
#187,799
of 289,007 outputs
Outputs of similar age from Frontiers in immunology
#192
of 503 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,520 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,007 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.