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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Unbalanced Neonatal CD4+ T-Cell Immunity
|
|---|---|
| Published in |
Frontiers in immunology, August 2014
|
| DOI | 10.3389/fimmu.2014.00393 |
| Pubmed ID | |
| Authors |
Isabelle Debock, Véronique Flamand |
| Abstract |
In comparison to adults, newborns display a heightened susceptibility to pathogens and a propensity to develop allergic diseases. Particular properties of the neonatal immune system can account for this sensitivity. Indeed, a defect in developing protective Th1-type responses and a skewing toward Th2 immunity characterize today the neonatal T-cell immunity. Recently, new findings concerning Th17, regulatory helper T-cell, and follicular helper T-cell subsets in newborns have emerged. In some circumstances, development of effector inflammatory Th17-type responses can be induced in neonates, while differentiation in regulatory T-cells appears to be a default program of neonatal CD4(+) T-cells. Poor antibody production, affinity maturation, and germinal center reaction in vaccinated neonates are correlated with a limiting expansion of TFH lymphocytes. We review herein the factors accounting for and the implications of the unbalanced neonatal helper T-cell immunity. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 33% |
| United States | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Australia | 1 | <1% |
| Canada | 1 | <1% |
| Mexico | 1 | <1% |
| Denmark | 1 | <1% |
| Spain | 1 | <1% |
| Venezuela, Bolivarian Republic of | 1 | <1% |
| Unknown | 168 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 41 | 23% |
| Student > Master | 25 | 14% |
| Student > Bachelor | 24 | 14% |
| Researcher | 20 | 11% |
| Student > Doctoral Student | 9 | 5% |
| Other | 18 | 10% |
| Unknown | 38 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 41 | 23% |
| Agricultural and Biological Sciences | 37 | 21% |
| Medicine and Dentistry | 26 | 15% |
| Biochemistry, Genetics and Molecular Biology | 21 | 12% |
| Nursing and Health Professions | 4 | 2% |
| Other | 7 | 4% |
| Unknown | 39 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2014.
All research outputs
#17,285,668
of 25,374,647 outputs
Outputs from Frontiers in immunology
#20,297
of 31,516 outputs
Outputs of similar age
#147,802
of 247,199 outputs
Outputs of similar age from Frontiers in immunology
#99
of 154 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,199 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.