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Priming of CD8+ T Cell Responses to Liver Stage Malaria Parasite Antigens

Overview of attention for article published in Frontiers in immunology, November 2014
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Title
Priming of CD8+ T Cell Responses to Liver Stage Malaria Parasite Antigens
Published in
Frontiers in immunology, November 2014
DOI 10.3389/fimmu.2014.00527
Pubmed ID
Authors

Giampietro Corradin, Jelena Levitskaya

Abstract

While the role of malaria parasite-specific memory CD8(+) T cells in the control of exo-erythrocytic stages of malaria infection is well documented and generally accepted, a debate is still ongoing regarding both the identity of the anatomic site where the activation of naive pathogen-specific T cells is taking place and contribution of different antigen-presenting cells (APCs) into this process. Whereas some studies infer a role of professional APCs present in the lymph nodes draining the site of parasite injection by the mosquito, others argue in favor of the liver as a primary organ and hepatocytes as stimulators of naïve parasite-specific T cell responses. This review aims to critically analyze the current knowledge and outline new lines of research necessary to understand the induction of protective cellular immunity against the malaria parasite.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Burkina Faso 1 2%
Netherlands 1 2%
India 1 2%
France 1 2%
Unknown 42 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 26%
Student > Ph. D. Student 6 13%
Student > Master 5 11%
Student > Postgraduate 4 9%
Student > Bachelor 3 7%
Other 8 17%
Unknown 8 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 26%
Immunology and Microbiology 8 17%
Biochemistry, Genetics and Molecular Biology 7 15%
Medicine and Dentistry 6 13%
Linguistics 2 4%
Other 4 9%
Unknown 7 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2014.
All research outputs
#21,500,619
of 26,391,552 outputs
Outputs from Frontiers in immunology
#25,797
of 33,103 outputs
Outputs of similar age
#205,058
of 277,095 outputs
Outputs of similar age from Frontiers in immunology
#154
of 193 outputs
Altmetric has tracked 26,391,552 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 33,103 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,095 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 193 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.