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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases
|
|---|---|
| Published in |
Frontiers in immunology, June 2015
|
| DOI | 10.3389/fimmu.2015.00322 |
| Pubmed ID | |
| Authors |
Christine Riedhammer, Robert Weissert |
| Abstract |
Antigen presentation is in the center of the immune system, both in host defense against pathogens, but also when the system is unbalanced and autoimmune diseases like multiple sclerosis (MS) develop. It is not just by chance that a major histocompatibility complex gene is the major genetic susceptibility locus in MS; a feature that MS shares with other autoimmune diseases. The exact etiology of the disease, however, has not been fully understood yet. T cells are regarded as the major players in the disease, but most probably a complex interplay of altered central and peripheral tolerance mechanisms, T-cell and B-cell functions, characteristics of putative autoantigens, and a possible interference of environmental factors like microorganisms are at work. In this review, new data on all these different aspects of antigen presentation and their role in MS will be discussed, probable autoantigens will be summarized, and comparisons to other autoimmune diseases will be drawn. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 20% |
| Germany | 1 | 20% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 225 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | <1% |
| Chile | 1 | <1% |
| Brazil | 1 | <1% |
| Canada | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 219 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 44 | 20% |
| Student > Ph. D. Student | 41 | 18% |
| Researcher | 31 | 14% |
| Student > Master | 27 | 12% |
| Student > Doctoral Student | 15 | 7% |
| Other | 29 | 13% |
| Unknown | 38 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 19% |
| Medicine and Dentistry | 37 | 16% |
| Immunology and Microbiology | 36 | 16% |
| Biochemistry, Genetics and Molecular Biology | 36 | 16% |
| Neuroscience | 8 | 4% |
| Other | 19 | 8% |
| Unknown | 47 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2022.
All research outputs
#5,678,201
of 26,178,577 outputs
Outputs from Frontiers in immunology
#6,492
of 32,859 outputs
Outputs of similar age
#64,027
of 278,279 outputs
Outputs of similar age from Frontiers in immunology
#36
of 171 outputs
Altmetric has tracked 26,178,577 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,859 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,279 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 171 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.