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How Neutrophils Shape Adaptive Immune Responses

Overview of attention for article published in Frontiers in immunology, September 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
1 news outlet
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4 X users

Citations

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189 Dimensions

Readers on

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346 Mendeley
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Title
How Neutrophils Shape Adaptive Immune Responses
Published in
Frontiers in immunology, September 2015
DOI 10.3389/fimmu.2015.00471
Pubmed ID
Authors

Pieter H. C. Leliefeld, Leo Koenderman, Janesh Pillay

Abstract

Neutrophils are classically considered as cells pivotal for the first line of defense against invading pathogens. In recent years, evidence has accumulated that they are also important in the orchestration of adaptive immunity. Neutrophils rapidly migrate in high numbers to sites of inflammation (e.g., infection, tissue damage, and cancer) and are subsequently able to migrate to draining lymph nodes (LNs). Both at the site of inflammation as well as in the LNs, neutrophils can engage with lymphocytes and antigen-presenting cells. This crosstalk occurs either directly via cell-cell contact or via mediators, such as proteases, cytokines, and radical oxygen species. In this review, we will discuss the current knowledge regarding locations and mechanisms of interaction between neutrophils and lymphocytes in the context of homeostasis and various pathological conditions. In addition, we will highlight the complexity of the microenvironment that is involved in the generation of suppressive or stimulatory neutrophil phenotypes.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 346 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 2 <1%
Austria 1 <1%
Australia 1 <1%
Sweden 1 <1%
Canada 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 338 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 67 19%
Researcher 58 17%
Student > Bachelor 48 14%
Student > Master 41 12%
Student > Doctoral Student 25 7%
Other 43 12%
Unknown 64 18%
Readers by discipline Count As %
Immunology and Microbiology 77 22%
Agricultural and Biological Sciences 61 18%
Medicine and Dentistry 57 16%
Biochemistry, Genetics and Molecular Biology 44 13%
Pharmacology, Toxicology and Pharmaceutical Science 7 2%
Other 30 9%
Unknown 70 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 August 2022.
All research outputs
#3,193,166
of 26,184,649 outputs
Outputs from Frontiers in immunology
#3,406
of 33,037 outputs
Outputs of similar age
#39,526
of 282,292 outputs
Outputs of similar age from Frontiers in immunology
#11
of 159 outputs
Altmetric has tracked 26,184,649 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 33,037 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,292 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 159 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.