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The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis

Overview of attention for article published in Frontiers in immunology, April 2016
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3 X users

Citations

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49 Dimensions

Readers on

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154 Mendeley
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Title
The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis
Published in
Frontiers in immunology, April 2016
DOI 10.3389/fimmu.2016.00153
Pubmed ID
Authors

Elisangela Oliveira de Freitas, Fabiana Maria de Souza Leoratti, Célio Geraldo Freire-de-Lima, Alexandre Morrot, Daniel Ferreira Feijó

Abstract

Leishmania is a genus of protozoan parasites that give rise to a range of diseases called Leishmaniasis that affects annually an estimated 1.3 million people from 88 countries. Leishmania donovani and Leishmania (L.) infantum chagasi are responsible to cause the visceral leishmaniasis. The parasite can use assorted strategies to interfere with the host homeostasis to establish persistent infections that without treatment can be lethal. In this review, we highlight the mechanisms involved in the parasite subversion of the host protective immune response and how alterations of host tissue physiology and vascular remodeling during VL could affect the organ-specific immunity against Leishmania parasites.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 154 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 153 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 29 19%
Student > Bachelor 22 14%
Student > Ph. D. Student 18 12%
Researcher 15 10%
Student > Doctoral Student 10 6%
Other 25 16%
Unknown 35 23%
Readers by discipline Count As %
Immunology and Microbiology 33 21%
Medicine and Dentistry 20 13%
Agricultural and Biological Sciences 19 12%
Biochemistry, Genetics and Molecular Biology 18 12%
Pharmacology, Toxicology and Pharmaceutical Science 9 6%
Other 14 9%
Unknown 41 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2016.
All research outputs
#16,970,566
of 25,932,719 outputs
Outputs from Frontiers in immunology
#18,621
of 32,608 outputs
Outputs of similar age
#182,232
of 314,651 outputs
Outputs of similar age from Frontiers in immunology
#81
of 134 outputs
Altmetric has tracked 25,932,719 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 32,608 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,651 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 134 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.