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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity
|
|---|---|
| Published in |
Frontiers in immunology, June 2016
|
| DOI | 10.3389/fimmu.2016.00233 |
| Pubmed ID | |
| Authors |
Benoît Stijlemans, Guy Caljon, Jan Van Den Abbeele, Jo A. Van Ginderachter, Stefan Magez, Carl De Trez |
| Abstract |
The diseases caused by African trypanosomes (AT) are of both medical and veterinary importance and have adversely influenced the economic development of sub-Saharan Africa. Moreover, so far not a single field applicable vaccine exists, and chemotherapy is the only strategy available to treat the disease. These strictly extracellular protozoan parasites are confronted with different arms of the host's immune response (cellular as well as humoral) and via an elaborate and efficient (vector)-parasite-host interplay they have evolved efficient immune escape mechanisms to evade/manipulate the entire host immune response. This is of importance, since these parasites need to survive sufficiently long in their mammalian/vector host in order to complete their life cycle/transmission. Here, we will give an overview of the different mechanisms AT (i.e. T. brucei as a model organism) employ, comprising both tsetse fly saliva and parasite-derived components to modulate host innate immune responses thereby sculpturing an environment that allows survival and development within the mammalian host. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 265 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ghana | 1 | <1% |
| Unknown | 264 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 48 | 18% |
| Student > Ph. D. Student | 43 | 16% |
| Student > Bachelor | 43 | 16% |
| Researcher | 30 | 11% |
| Other | 8 | 3% |
| Other | 32 | 12% |
| Unknown | 61 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 69 | 26% |
| Agricultural and Biological Sciences | 46 | 17% |
| Immunology and Microbiology | 36 | 14% |
| Medicine and Dentistry | 15 | 6% |
| Veterinary Science and Veterinary Medicine | 10 | 4% |
| Other | 24 | 9% |
| Unknown | 65 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2016.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Frontiers in immunology
#24,741
of 31,516 outputs
Outputs of similar age
#284,208
of 368,667 outputs
Outputs of similar age from Frontiers in immunology
#100
of 122 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,667 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.