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GATA3 Regulates the Development and Functions of Innate Lymphoid Cell Subsets at Multiple Stages

Overview of attention for article published in Frontiers in immunology, November 2017
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  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

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4 X users
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1 Wikipedia page

Citations

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63 Dimensions

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Title
GATA3 Regulates the Development and Functions of Innate Lymphoid Cell Subsets at Multiple Stages
Published in
Frontiers in immunology, November 2017
DOI 10.3389/fimmu.2017.01571
Pubmed ID
Authors

Jinfang Zhu

Abstract

Innate lymphoid cells (ILCs) are regarded as the innate counterpart of effector CD4 T helper (Th) cells. Just as Th cells, ILCs are classified into distinct subsets based on their functions that are delivered mainly through effector cytokine production. Both ILCs and Th cells play critical roles in various protective immune responses and inflammatory diseases. Similar to Th cell differentiation, the development of ILC subsets depends on several master transcription factors, among which GATA3 is critical for the development and maintenance of type 2 ILCs (ILC2s). However, GATA3 is expressed by all ILC subsets and ILC progenitors, albeit at different levels. In a striking parallel with GATA3 function in T cell development and differentiation, GATA3 also has multiple functions in different ILCs at various stages. In this review, I will discuss how quantitative and dynamic expression of GATA3 regulates the development and functions of ILC subsets.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 72 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 17%
Student > Master 9 13%
Researcher 8 11%
Student > Doctoral Student 7 10%
Student > Bachelor 4 6%
Other 8 11%
Unknown 24 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 24%
Immunology and Microbiology 16 22%
Medicine and Dentistry 7 10%
Agricultural and Biological Sciences 4 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 1 1%
Unknown 25 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2018.
All research outputs
#6,932,988
of 25,382,440 outputs
Outputs from Frontiers in immunology
#7,408
of 31,537 outputs
Outputs of similar age
#103,489
of 336,130 outputs
Outputs of similar age from Frontiers in immunology
#175
of 574 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,130 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 574 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.