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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Inhibiting the Ins and Outs of HIV Replication: Cell-Intrinsic Antiretroviral Restrictions at the Plasma Membrane
|
|---|---|
| Published in |
Frontiers in immunology, January 2018
|
| DOI | 10.3389/fimmu.2017.01853 |
| Pubmed ID | |
| Authors |
Toshana L. Foster, Suzanne Pickering, Stuart J. D. Neil |
| Abstract |
Like all viruses, human immunodeficiency viruses (HIVs) and their primate lentivirus relatives must enter cells in order to replicate and, once produced, new virions need to exit to spread to new targets. These processes require the virus to cross the plasma membrane of the cell twice: once via fusion mediated by the envelope glycoprotein to deliver the viral core into the cytosol; and secondly by ESCRT-mediated scission of budding virions during release. This physical barrier thus presents a perfect location for host antiviral restrictions that target enveloped viruses in general. In this review we will examine the current understanding of innate host antiviral defences that inhibit these essential replicative steps of primate lentiviruses associated with the plasma membrane, the mechanism by which these viruses have adapted to evade such defences, and the role that this virus/host battleground plays in the transmission and pathogenesis of HIV/AIDS. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 17% |
| Australia | 1 | 17% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 55 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 20% |
| Researcher | 10 | 18% |
| Student > Master | 9 | 16% |
| Student > Bachelor | 7 | 13% |
| Student > Doctoral Student | 4 | 7% |
| Other | 5 | 9% |
| Unknown | 9 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 15 | 27% |
| Biochemistry, Genetics and Molecular Biology | 13 | 24% |
| Agricultural and Biological Sciences | 8 | 15% |
| Medicine and Dentistry | 5 | 9% |
| Computer Science | 1 | 2% |
| Other | 3 | 5% |
| Unknown | 10 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2022.
All research outputs
#15,279,596
of 26,414,132 outputs
Outputs from Frontiers in immunology
#13,079
of 33,172 outputs
Outputs of similar age
#230,536
of 456,948 outputs
Outputs of similar age from Frontiers in immunology
#319
of 600 outputs
Altmetric has tracked 26,414,132 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 33,172 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 456,948 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 600 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.