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X Demographics
Mendeley readers
Attention Score in Context
Title |
Next-Generation Sequencing of Antibody Display Repertoires
|
---|---|
Published in |
Frontiers in immunology, February 2018
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DOI | 10.3389/fimmu.2018.00118 |
Pubmed ID | |
Authors |
Romain Rouet, Katherine J. L. Jackson, David B. Langley, Daniel Christ |
Abstract |
In vitro selection technology has transformed the development of therapeutic monoclonal antibodies. Using methods such as phage, ribosome, and yeast display, high affinity binders can be selected from diverse repertoires. Here, we review strategies for the next-generation sequencing (NGS) of phage- and other antibody-display libraries, as well as NGS platforms and analysis tools. Moreover, we discuss recent examples relating to the use of NGS to assess library diversity, clonal enrichment, and affinity maturation. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 262 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 262 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 54 | 21% |
Student > Ph. D. Student | 45 | 17% |
Student > Master | 30 | 11% |
Other | 21 | 8% |
Student > Doctoral Student | 13 | 5% |
Other | 32 | 12% |
Unknown | 67 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 74 | 28% |
Agricultural and Biological Sciences | 45 | 17% |
Immunology and Microbiology | 29 | 11% |
Chemical Engineering | 6 | 2% |
Chemistry | 6 | 2% |
Other | 28 | 11% |
Unknown | 74 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2023.
All research outputs
#8,264,793
of 25,382,440 outputs
Outputs from Frontiers in immunology
#10,116
of 31,537 outputs
Outputs of similar age
#156,502
of 448,179 outputs
Outputs of similar age from Frontiers in immunology
#283
of 646 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 448,179 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 646 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.