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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Reinforcing the Functionality of Mononuclear Phagocyte System to Control Tuberculosis
|
|---|---|
| Published in |
Frontiers in immunology, February 2018
|
| DOI | 10.3389/fimmu.2018.00193 |
| Pubmed ID | |
| Authors |
Susanta Pahari, Gurpreet Kaur, Shikha Negi, Mohammad Aqdas, Deepjyoti K. Das, Hilal Bashir, Sanpreet Singh, Mukta Nagare, Junaid Khan, Javed N. Agrewala |
| Abstract |
The mononuclear phagocyte system (MPS) constitutes dendritic cells, monocytes, and macrophages. This system contributes to various functions that are essential for maintaining homeostasis, activation of innate immunity, and bridging it with the adaptive immunity. Consequently, MPS is highly important in bolstering immunity against the pathogens. However, MPS is the frontline cells in destroyingMycobacterium tuberculosis(Mtb), yet the bacterium prefers to reside in the hostile environment of macrophages. Therefore, it may be very interesting to study the struggle betweenMtband MPS to understand the outcome of the disease. In an event when MPS predominatesMtb, the host remains protected. By contrast, the situation becomes devastating when the pathogen tames and tunes the host MPS, which ultimately culminates into tuberculosis (TB). Hence, it becomes extremely crucial to reinvigorate MPS functionality to overwhelmMtband eliminate it. In this article, we discuss the strategies to bolster the function of MPS by exploiting the molecules associated with the innate immunity and highlight the mechanisms involved to overcome theMtb-induced suppression of host immunity. In future, such approaches may provide an insight to develop immunotherapeutics to treat TB. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| France | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 63 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 21% |
| Student > Bachelor | 10 | 16% |
| Student > Ph. D. Student | 5 | 8% |
| Student > Doctoral Student | 4 | 6% |
| Researcher | 4 | 6% |
| Other | 8 | 13% |
| Unknown | 19 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 25% |
| Immunology and Microbiology | 11 | 17% |
| Medicine and Dentistry | 5 | 8% |
| Agricultural and Biological Sciences | 3 | 5% |
| Environmental Science | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 21 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2018.
All research outputs
#8,081,098
of 26,184,649 outputs
Outputs from Frontiers in immunology
#9,497
of 33,037 outputs
Outputs of similar age
#150,815
of 456,780 outputs
Outputs of similar age from Frontiers in immunology
#256
of 640 outputs
Altmetric has tracked 26,184,649 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 33,037 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 456,780 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 640 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.