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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Dectin-1-Syk-CARD9 Signaling Pathway in TB Immunity
|
|---|---|
| Published in |
Frontiers in immunology, February 2018
|
| DOI | 10.3389/fimmu.2018.00225 |
| Pubmed ID | |
| Authors |
Matthew Wagener, J. Claire Hoving, Hlumani Ndlovu, Mohlopheni J. Marakalala |
| Abstract |
One of the first steps toward mounting an effective immune response toMycobacterium tuberculosis(Mtb) is recognition of the pathogen through pattern-recognition receptors (PRRs) expressed by innate immune cells. Activation of the PRR Dectin-1 by an unknown mycobacterial ligand triggers an intracellular signaling cascade involving numerous proteins, including spleen tyrosine kinase, protein kinase C-delta, and caspase recruitment domain family member 9, some of which have been shown to influence host immune response to TB infection. Here, we review the role of Dectin-1 signaling pathway in anti-mycobacterial immunity and discuss its contribution in the control of Mtb infection, and potential applications in TB vaccine adjuvanticity. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 2 | 33% |
| United Kingdom | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 115 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 17% |
| Student > Master | 14 | 12% |
| Researcher | 12 | 10% |
| Student > Bachelor | 12 | 10% |
| Student > Doctoral Student | 6 | 5% |
| Other | 14 | 12% |
| Unknown | 37 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 20 | 17% |
| Agricultural and Biological Sciences | 17 | 15% |
| Immunology and Microbiology | 17 | 15% |
| Medicine and Dentistry | 5 | 4% |
| Nursing and Health Professions | 4 | 3% |
| Other | 14 | 12% |
| Unknown | 38 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2023.
All research outputs
#3,218,907
of 25,523,622 outputs
Outputs from Frontiers in immunology
#3,399
of 31,887 outputs
Outputs of similar age
#72,128
of 456,116 outputs
Outputs of similar age from Frontiers in immunology
#107
of 664 outputs
Altmetric has tracked 25,523,622 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,887 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 456,116 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 664 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.