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Visualizing the Immune System: Providing Key Insights into HIV/SIV Infections

Overview of attention for article published in Frontiers in immunology, March 2018
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3 X users

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17 Dimensions

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38 Mendeley
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Title
Visualizing the Immune System: Providing Key Insights into HIV/SIV Infections
Published in
Frontiers in immunology, March 2018
DOI 10.3389/fimmu.2018.00423
Pubmed ID
Authors

Jacob D. Estes, Roger LeGrand, Constantinos Petrovas

Abstract

Immunological inductive tissues, such as secondary lymphoid organs, are composed of distinct anatomical microenvironments for the generation of immune responses to pathogens and immunogens. These microenvironments are characterized by the compartmentalization of highly specialized immune and stromal cell populations, as well as the presence of a complex network of soluble factors and chemokines that direct the intra-tissue trafficking of naïve and effector cell populations. Imaging platforms have provided critical contextual information regarding the molecular and cellular interactions that orchestrate the spatial microanatomy of relevant cells and the development of immune responses against pathogens. Particularly in HIV/SIV disease, imaging technologies are of great importance in the investigation of the local interplay between the virus and host cells, with respect to understanding viral dynamics and persistence, immune responses (i.e., adaptive and innate inflammatory responses), tissue structure and pathologies, and changes to the surrounding milieu and function of immune cells. Merging imaging platforms with other cutting-edge technologies could lead to novel findings regarding the phenotype, function, and molecular signatures of particular immune cell targets, further promoting the development of new antiviral treatments and vaccination strategies.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 16%
Student > Ph. D. Student 5 13%
Student > Bachelor 4 11%
Researcher 4 11%
Student > Postgraduate 4 11%
Other 4 11%
Unknown 11 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 16%
Agricultural and Biological Sciences 6 16%
Medicine and Dentistry 4 11%
Immunology and Microbiology 3 8%
Chemistry 2 5%
Other 4 11%
Unknown 13 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2018.
All research outputs
#15,175,718
of 25,382,440 outputs
Outputs from Frontiers in immunology
#14,217
of 31,537 outputs
Outputs of similar age
#184,300
of 346,135 outputs
Outputs of similar age from Frontiers in immunology
#393
of 692 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 346,135 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 692 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.