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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases
|
|---|---|
| Published in |
Frontiers in immunology, May 2018
|
| DOI | 10.3389/fimmu.2018.00832 |
| Pubmed ID | |
| Authors |
Serge Grazioli, Jérôme Pugin |
| Abstract |
Over the recent years, much has been unraveled about the pro-inflammatory properties of various mitochondrial molecules once they are leaving the mitochondrial compartment. On entering the cytoplasm or the extracellular space, mitochondrial DAMPs (also known as mitochondrial alarmins) can become pro-inflammatory and initiate innate and adaptive immune responses by activating cell surface and intracellular receptors. Current evidence indicates that uncontrolled and excessive release of mitochondrial DAMPs is associated with severity, has prognosis value in human diseases, and contributes to the dysregulated process observed in numerous inflammatory and autoimmune conditions, as well as in ischemic heart disease and cancer. Herein, we review that the expanding research field of mitochondrial DAMPs in innate immune responses and the current knowledge on the association between mitochondrial DAMPs and human diseases. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 15% |
| Switzerland | 2 | 6% |
| United Kingdom | 1 | 3% |
| Korea, Republic of | 1 | 3% |
| Singapore | 1 | 3% |
| Canada | 1 | 3% |
| Unknown | 23 | 68% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 25 | 74% |
| Scientists | 8 | 24% |
| Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 246 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 246 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 42 | 17% |
| Student > Master | 32 | 13% |
| Student > Bachelor | 30 | 12% |
| Researcher | 25 | 10% |
| Student > Doctoral Student | 18 | 7% |
| Other | 31 | 13% |
| Unknown | 68 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 52 | 21% |
| Medicine and Dentistry | 32 | 13% |
| Agricultural and Biological Sciences | 23 | 9% |
| Immunology and Microbiology | 18 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 5% |
| Other | 31 | 13% |
| Unknown | 77 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2024.
All research outputs
#2,166,408
of 26,538,386 outputs
Outputs from Frontiers in immunology
#2,142
of 33,362 outputs
Outputs of similar age
#42,806
of 344,142 outputs
Outputs of similar age from Frontiers in immunology
#61
of 714 outputs
Altmetric has tracked 26,538,386 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 33,362 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,142 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 714 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.