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Biochemistry of microbial itaconic acid production

Overview of attention for article published in Frontiers in Microbiology, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

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1 news outlet
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1 X user
wikipedia
2 Wikipedia pages

Citations

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150 Dimensions

Readers on

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354 Mendeley
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Title
Biochemistry of microbial itaconic acid production
Published in
Frontiers in Microbiology, January 2013
DOI 10.3389/fmicb.2013.00023
Pubmed ID
Authors

Matthias G. Steiger, Marzena L. Blumhoff, Diethard Mattanovich, Michael Sauer

Abstract

Itaconic acid is an unsaturated dicarbonic acid which has a high potential as a biochemical building block, because it can be used as a monomer for the production of a plethora of products including resins, plastics, paints, and synthetic fibers. Some Aspergillus species, like A. itaconicus and A. terreus, show the ability to synthesize this organic acid and A. terreus can secrete significant amounts to the media (>80 g/L). However, compared with the citric acid production process (titers >200 g/L) the achieved titers are still low and the overall process is expensive because purified substrates are required for optimal productivity. Itaconate is formed by the enzymatic activity of a cis-aconitate decarboxylase (CadA) encoded by the cadA gene in A. terreus. Cloning of the cadA gene into the citric acid producing fungus A. niger showed that it is possible to produce itaconic acid also in a different host organism. This review will describe the current status and recent advances in the understanding of the molecular processes leading to the biotechnological production of itaconic acid.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 354 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 <1%
Spain 2 <1%
Hungary 1 <1%
Netherlands 1 <1%
Denmark 1 <1%
Brazil 1 <1%
China 1 <1%
United States 1 <1%
Unknown 343 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 65 18%
Student > Ph. D. Student 58 16%
Student > Bachelor 49 14%
Researcher 46 13%
Student > Doctoral Student 14 4%
Other 56 16%
Unknown 66 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 84 24%
Biochemistry, Genetics and Molecular Biology 64 18%
Chemistry 32 9%
Chemical Engineering 26 7%
Engineering 23 6%
Other 45 13%
Unknown 80 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2020.
All research outputs
#2,403,378
of 22,696,971 outputs
Outputs from Frontiers in Microbiology
#1,977
of 24,508 outputs
Outputs of similar age
#25,537
of 280,682 outputs
Outputs of similar age from Frontiers in Microbiology
#38
of 407 outputs
Altmetric has tracked 22,696,971 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,508 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,682 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 407 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.