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Adhesion, biofilm formation, cell surface hydrophobicity, and antifungal planktonic susceptibility: relationship among Candida spp.

Overview of attention for article published in Frontiers in Microbiology, March 2015
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3 X users

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171 Dimensions

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226 Mendeley
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Title
Adhesion, biofilm formation, cell surface hydrophobicity, and antifungal planktonic susceptibility: relationship among Candida spp.
Published in
Frontiers in Microbiology, March 2015
DOI 10.3389/fmicb.2015.00205
Pubmed ID
Authors

Ana Silva-Dias, Isabel M. Miranda, Joana Branco, Matilde Monteiro-Soares, Cidália Pina-Vaz, Acácio G. Rodrigues

Abstract

We have performed the characterization of the adhesion profile, biofilm formation, cell surface hydrophobicity (CSH) and antifungal susceptibility of 184 Candida clinical isolates obtained from different human reservoirs. Adhesion was quantified using a flow cytometric assay and biofilm formation was evaluated using two methodologies: XTT and crystal violet assay. CSH was quantified with the microbial adhesion to hydrocarbons test while planktonic susceptibility was assessed accordingly the CLSI protocol for yeast M27-A3 S4. Yeast cells of non-albicans species exhibit increased ability to adhere and form biofilm. However, the correlation between adhesion and biofilm formation varied according to species and also with the methodology used for biofilm assessment. No association was found between strain's site of isolation or planktonic antifungal susceptibility and adhesion or biofilm formation. Finally CSH seemed to be a good predictor for biofilm formation but not for adhesion. Despite the marked variability registered intra and inter species, C. tropicalis and C. parapsilosis were the species exhibiting high adhesion profile. C. tropicalis, C. guilliermondii, and C. krusei revealed higher biofilm formation values in terms of biomass. C. parapsilosis was the species with lower biofilm metabolic activity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 226 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 <1%
Czechia 1 <1%
Spain 1 <1%
Unknown 222 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 51 23%
Student > Ph. D. Student 44 19%
Student > Doctoral Student 28 12%
Student > Bachelor 18 8%
Researcher 13 6%
Other 23 10%
Unknown 49 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 45 20%
Biochemistry, Genetics and Molecular Biology 32 14%
Immunology and Microbiology 27 12%
Medicine and Dentistry 19 8%
Engineering 9 4%
Other 26 12%
Unknown 68 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 March 2015.
All research outputs
#14,805,023
of 22,794,367 outputs
Outputs from Frontiers in Microbiology
#13,779
of 24,732 outputs
Outputs of similar age
#145,148
of 259,041 outputs
Outputs of similar age from Frontiers in Microbiology
#171
of 307 outputs
Altmetric has tracked 22,794,367 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,732 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 259,041 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 307 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.