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Helicobacter pylori neutrophil-activating protein: a potential Treg modulator suppressing allergic asthma?

Overview of attention for article published in Frontiers in Microbiology, June 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

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1 blog
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4 X users

Citations

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33 Mendeley
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Title
Helicobacter pylori neutrophil-activating protein: a potential Treg modulator suppressing allergic asthma?
Published in
Frontiers in Microbiology, June 2015
DOI 10.3389/fmicb.2015.00493
Pubmed ID
Authors

Anjna Sehrawat, Siddharth Sinha, Abhishek Saxena

Abstract

The ultimate aim of the immune system is to eliminate pathogens without being harmful to the host. But what if eliminating the pathogen in itself is discomforting for the host? One such emerging case is of Helicobacter pylori. Modern medicine, infantile vaccination, and ultra-hygienic conditions have led to progressive disappearance of H. pylori in different parts of the world. However, the adversities caused by H. pylori's absence are much larger than those caused by its presence. Asthma is rising as an epidemic in last few decades and several reports suggest an inverse-relationship between H. pylori's persistence and early-life onset asthma. Regulatory T cells play an important role in both the cases. This is further supported by experiments on mouse-models. Hence, need of the hour is to discern the relationship between H. pylori and its host and eliminating its negative impacts without disturbing our indigenous microbiota. To resolve whether H. pylori is a pathogen or an amphibiont is another important side. This review explores the biological basis of H. pylori-induced priming of immune system offering resistance to childhood-onset asthma. HP-NAP-Tregs interaction has been predicted using molecular docking and dynamic simulation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 32 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 15%
Researcher 4 12%
Student > Bachelor 4 12%
Student > Doctoral Student 3 9%
Professor > Associate Professor 3 9%
Other 8 24%
Unknown 6 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 18%
Medicine and Dentistry 6 18%
Immunology and Microbiology 6 18%
Agricultural and Biological Sciences 4 12%
Nursing and Health Professions 1 3%
Other 3 9%
Unknown 7 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2018.
All research outputs
#3,750,132
of 25,307,332 outputs
Outputs from Frontiers in Microbiology
#3,533
of 29,054 outputs
Outputs of similar age
#46,531
of 273,985 outputs
Outputs of similar age from Frontiers in Microbiology
#42
of 388 outputs
Altmetric has tracked 25,307,332 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 29,054 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,985 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 388 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.