Title |
Broad-spectrum antiviral agents
|
---|---|
Published in |
Frontiers in Microbiology, May 2015
|
DOI | 10.3389/fmicb.2015.00517 |
Pubmed ID | |
Authors |
Jun-Da Zhu, Wen Meng, Xiao-Jia Wang, Hwa-Chain R. Wang |
Abstract |
Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular defense system. High throughput screening of molecules, genetic engineering of peptides, and functional screening of agents have identified promising candidates for development of optimal broad-spectrum antiviral agents to intervene in viral infection and control viral epidemics. This review discusses current knowledge, prospective applications, opportunities, and challenges in the development of broad-spectrum antiviral agents. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Denmark | 1 | <1% |
Unknown | 200 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 35 | 17% |
Researcher | 31 | 15% |
Student > Master | 28 | 14% |
Student > Bachelor | 19 | 9% |
Student > Doctoral Student | 15 | 7% |
Other | 25 | 12% |
Unknown | 48 | 24% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 42 | 21% |
Agricultural and Biological Sciences | 29 | 14% |
Immunology and Microbiology | 15 | 7% |
Chemistry | 14 | 7% |
Medicine and Dentistry | 14 | 7% |
Other | 30 | 15% |
Unknown | 57 | 28% |