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Challenges and perspectives in combinatorial assembly of novel exopolysaccharide biosynthesis pathways

Overview of attention for article published in Frontiers in Microbiology, July 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

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3 X users
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1 Wikipedia page

Citations

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54 Dimensions

Readers on

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117 Mendeley
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Title
Challenges and perspectives in combinatorial assembly of novel exopolysaccharide biosynthesis pathways
Published in
Frontiers in Microbiology, July 2015
DOI 10.3389/fmicb.2015.00687
Pubmed ID
Authors

Anke Becker

Abstract

Because of their rheological properties various microbial polysaccharides are applied as thickeners and viscosifiers both in food and non-food industries. A broad variety of microorganisms secrete structurally diverse exopolysaccharides (EPS) that contribute to their surface attachment, protection against abiotic or biotic stress factors, and nutrient gathering. Theoretically, a massive number of EPS structures are possible through variations in monosaccharide sequences, condensation linkages and non-sugar decorations. Given the already-high diversity of EPS structures, taken together with the principal of combinatorial biosynthetic pathways, microbial polysaccharides are an attractive class of macromolecules with which to generate novel structures via synthetic biology approaches. However, previous manipulations primarily focused on increasing polysaccharide yield, with structural modifications restricted to removal of side chains or non-sugar decorations. This article outlines the biosynthetic pathways of the bacterial heteroexopolysaccharides xanthan and succinoglycan, which are used as thickening and stabilizing agents in food and non-food industries. Challenges and perspectives of combining synthetic biology approaches with directed evolution to overcome obstacles in assembly of novel EPS biosynthesis pathways are discussed.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 <1%
Denmark 1 <1%
Brazil 1 <1%
Unknown 114 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 19 16%
Researcher 17 15%
Student > Bachelor 15 13%
Student > Ph. D. Student 14 12%
Student > Postgraduate 8 7%
Other 17 15%
Unknown 27 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 26%
Biochemistry, Genetics and Molecular Biology 29 25%
Immunology and Microbiology 10 9%
Chemistry 5 4%
Engineering 5 4%
Other 10 9%
Unknown 28 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2020.
All research outputs
#6,795,137
of 22,816,807 outputs
Outputs from Frontiers in Microbiology
#6,898
of 24,773 outputs
Outputs of similar age
#78,370
of 262,224 outputs
Outputs of similar age from Frontiers in Microbiology
#98
of 345 outputs
Altmetric has tracked 22,816,807 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 24,773 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,224 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 345 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.