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Participation of Leukotrienes in the Immune Modulation of Oral Tolerance

Overview of attention for article published in Frontiers in Microbiology, February 2017
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Title
Participation of Leukotrienes in the Immune Modulation of Oral Tolerance
Published in
Frontiers in Microbiology, February 2017
DOI 10.3389/fmicb.2017.00242
Pubmed ID
Authors

Sandra R. P. de Oliveira, Auro Nomizo, Fabiani G. Frantz, Lúcia H. Faccioli, Ana Paula Keller de Matos, Emanuel Carrilho, Ana Afonso, Fernanda de Freitas Anibal

Abstract

Oral tolerance (OT) is characterized as a peripheral immune tolerance form, in which, mature lymphocytes in lymphoid tissues associated with mucosa, become non-functional or hypo responsive due to prior oral administration of antigen. OT is an important immunological phenomenon due to its therapeutic potential in inflammatory processes and others diseases. Here we evaluated leukotriene role in the induction of OT, as well as, the production of cytokines IL-5 and IFN-γ in leukotriene deficient animals (knock-out). Our results suggested that even in the presence of OT and leukotrienes absence, cytokine IFN-γ remains being secreted, which gives us an indication of immune system specificity and also that IFN-γ participates in various immune processes.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 3 27%
Student > Bachelor 2 18%
Professor 2 18%
Student > Master 1 9%
Student > Doctoral Student 1 9%
Other 0 0%
Unknown 2 18%
Readers by discipline Count As %
Immunology and Microbiology 3 27%
Biochemistry, Genetics and Molecular Biology 2 18%
Nursing and Health Professions 2 18%
Pharmacology, Toxicology and Pharmaceutical Science 1 9%
Chemistry 1 9%
Other 0 0%
Unknown 2 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 February 2017.
All research outputs
#15,447,117
of 22,955,959 outputs
Outputs from Frontiers in Microbiology
#15,250
of 24,987 outputs
Outputs of similar age
#197,462
of 310,778 outputs
Outputs of similar age from Frontiers in Microbiology
#311
of 448 outputs
Altmetric has tracked 22,955,959 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,987 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,778 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 448 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.