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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of Modulator of Inflammation Cyclooxygenase-2 in Gammaherpesvirus Mediated Tumorigenesis
|
|---|---|
| Published in |
Frontiers in Microbiology, March 2017
|
| DOI | 10.3389/fmicb.2017.00538 |
| Pubmed ID | |
| Authors |
Jaya Gandhi, Lohit Khera, Nivedita Gaur, Catherine Paul, Rajeev Kaul |
| Abstract |
Chronic inflammation is recognized as a threat factor for cancer progression. Release of inflammatory molecules generates microenvironment which is highly favorable for development of tumor, cancer progression and metastasis. In cases of latent viral infections, generation of such a microenvironment is one of the major predisposing factors related to virus mediated tumorigenesis. Among various inflammatory mediators implicated in pathological process associated with cancer, the cyclooxygenase (COX) and its downstream effector molecules are of greater significance. Though the role of infectious agents in causing inflammation leading to transformation of cells has been more or less well established, however, the mechanism by which inflammation in itself modulates the events in life cycle of infectious agent is not very much clear. This is specifically important for gammaherpesviruses infections where viral life cycle is characterized by prolonged periods of latency when the virus remains hidden, immunologically undetectable and expresses only a very limited set of genes. Therefore, it is important to understand the mechanisms for role of inflammation in virus life cycle and tumorigenesis. This review is an attempt to summarize the latest findings highlighting the significance of COX-2 and its downstream signaling effectors role in life cycle events of gammaherpesviruses leading to progression of cancer. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 144 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 144 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 26 | 18% |
| Student > Master | 19 | 13% |
| Student > Ph. D. Student | 15 | 10% |
| Researcher | 7 | 5% |
| Student > Doctoral Student | 6 | 4% |
| Other | 17 | 12% |
| Unknown | 54 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 19 | 13% |
| Biochemistry, Genetics and Molecular Biology | 19 | 13% |
| Agricultural and Biological Sciences | 10 | 7% |
| Chemistry | 9 | 6% |
| Medicine and Dentistry | 9 | 6% |
| Other | 21 | 15% |
| Unknown | 57 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2023.
All research outputs
#20,867,311
of 26,508,329 outputs
Outputs from Frontiers in Microbiology
#20,065
of 30,401 outputs
Outputs of similar age
#239,355
of 327,248 outputs
Outputs of similar age from Frontiers in Microbiology
#393
of 491 outputs
Altmetric has tracked 26,508,329 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 30,401 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,248 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 491 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.