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Characterization of Mycobacterium chelonae-Like Strains by Comparative Genomics

Overview of attention for article published in Frontiers in Microbiology, May 2017
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  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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2 X users
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1 Wikipedia page

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7 Dimensions

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21 Mendeley
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Title
Characterization of Mycobacterium chelonae-Like Strains by Comparative Genomics
Published in
Frontiers in Microbiology, May 2017
DOI 10.3389/fmicb.2017.00789
Pubmed ID
Authors

Christiane L. Nogueira, Luiz G. P. de Almeida, Maria C. Menendez, Maria J. Garcia, Luciano A. Digiampietri, Erica Chimara, Margo Cnockaert, Juan C. Palomino, Françoise Portaels, Anandi Martin, Peter Vandamme, Sylvia C. Leão

Abstract

Isolates of the Mycobacterium chelonae-M. abscessus complex are subdivided into four clusters (CHI to CHIV) in the INNO-LiPA® Mycobacterium spp DNA strip assay. A considerable phenotypic variability was observed among isolates of the CHII cluster. In this study, we examined the diversity of 26 CHII cluster isolates by phenotypic analysis, drug susceptibility testing, whole genome sequencing and single-gene analysis. Pairwise genome comparisons were performed using several approaches, including average nucleotide identity (ANI) and genome-to-genome distance (GGD) among others. Based on ANI and GGD the isolates were identified as M. chelonae (14 isolates), M. franklinii (2 isolates) and M. salmoniphium (1 isolate). The remaining 9 isolates were subdivided into three novel putative genomospecies. Phenotypic analyses including drug susceptibility testing, as well as whole genome comparison by TETRA and delta differences, were not helpful in separating the groups revealed by ANI and GGD. The analysis of standard four conserved genomic regions showed that rpoB alone and the concatenated sequences clearly distinguished the taxonomic groups delimited by whole genome analyses. In conclusion, the CHII INNO-LiPa is not a homogeneous cluster; on the contrary, it is composed of closely related different species belonging to the M. chelonae-M. abscessus complex and also several unidentified isolates. The detection of these isolates, putatively novel species, indicates a wider inner variability than the presently known in this complex.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 24%
Researcher 4 19%
Other 2 10%
Student > Bachelor 2 10%
Professor 1 5%
Other 2 10%
Unknown 5 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 24%
Biochemistry, Genetics and Molecular Biology 4 19%
Medicine and Dentistry 2 10%
Immunology and Microbiology 2 10%
Environmental Science 1 5%
Other 1 5%
Unknown 6 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2022.
All research outputs
#6,574,236
of 23,986,470 outputs
Outputs from Frontiers in Microbiology
#6,376
of 26,947 outputs
Outputs of similar age
#99,774
of 313,754 outputs
Outputs of similar age from Frontiers in Microbiology
#210
of 512 outputs
Altmetric has tracked 23,986,470 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 26,947 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,754 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 512 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.