The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Timeline
Mendeley readers
| Title |
Efficacy of Cefquinome against Escherichia coli Environmental Mastitis Assessed by Pharmacokinetic and Pharmacodynamic Integration in Lactating Mouse Model
|
|---|---|
| Published in |
Frontiers in Microbiology, August 2017
|
| DOI | 10.3389/fmicb.2017.01445 |
| Pubmed ID | |
| Authors |
Yang Yu, Jin-Tao Fang, Jian Sun, Mei Zheng, Qing Zhang, Jie-Shun He, Xiao-Ping Liao, Ya-Hong Liu |
| Abstract |
This work investigates the pharmacodynamic effectiveness of cefquinome against environmental Escherichia coli mastitis infection, following an intramammary administration. We established the pharmacokinetic and pharmacodynamic (PK/PD) model in lactating mice. The PK/PD parameters were identified to achieve an antibacterial efficacy as indicated by PD activity, cytokine expression and PK/PD simulation. From our findings, given an 200 μg/gland dose once daily can achieve a considerable therapeutic effectiveness in experimental circumstance. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 23 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 5 | 22% |
| Student > Ph. D. Student | 3 | 13% |
| Student > Doctoral Student | 2 | 9% |
| Researcher | 2 | 9% |
| Lecturer > Senior Lecturer | 1 | 4% |
| Other | 3 | 13% |
| Unknown | 7 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Veterinary Science and Veterinary Medicine | 3 | 13% |
| Agricultural and Biological Sciences | 3 | 13% |
| Immunology and Microbiology | 2 | 9% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Nursing and Health Professions | 1 | 4% |
| Other | 4 | 17% |
| Unknown | 9 | 39% |