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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Alterations in the Spectrum of Spontaneous Rifampicin-Resistance Mutations in the Bacillus subtilis rpoB Gene after Cultivation in the Human Spaceflight Environment
|
|---|---|
| Published in |
Frontiers in Microbiology, February 2018
|
| DOI | 10.3389/fmicb.2018.00192 |
| Pubmed ID | |
| Authors |
Patricia Fajardo-Cavazos, Joshua D. Leehan, Wayne L. Nicholson |
| Abstract |
The effect ofBacillus subtilisexposure to the human spaceflight environment on growth, mutagenic frequency, and spectrum of mutations to rifampicin resistance (RifR) was investigated.B. subtiliscells were cultivated in Biological Research in Canister-Petri Dish Fixation Units (BRIC-PDFUs) on two separate missions to the International Space Station (ISS), dubbed BRIC-18 and BRIC-21, with matching asynchronous ground controls. No statistically significant difference in either growth or in the frequency of mutation to RifRwas found in either experiment. However, nucleotide sequencing of the RifRregions of therpoBgene from RifRmutants revealed dramatic differences in the spectrum of mutations between flight (FL) and ground control (GC) samples, including two newly discoveredrpoBalleles in the FL samples (Q137R and L489S). The results strengthen the idea that exposure to the human spaceflight environment causes unique stresses on bacteria, leading to alterations in their mutagenic potential. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 25% |
| Student > Ph. D. Student | 4 | 13% |
| Student > Bachelor | 3 | 9% |
| Student > Master | 2 | 6% |
| Professor | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 12 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 19% |
| Medicine and Dentistry | 5 | 16% |
| Computer Science | 3 | 9% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Chemical Engineering | 1 | 3% |
| Other | 4 | 13% |
| Unknown | 11 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2018.
All research outputs
#17,932,482
of 23,025,074 outputs
Outputs from Frontiers in Microbiology
#17,430
of 25,149 outputs
Outputs of similar age
#314,784
of 446,267 outputs
Outputs of similar age from Frontiers in Microbiology
#428
of 558 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,149 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,267 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 558 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.