You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mechanism of Anti-bacterial Activity of Zinc Oxide Nanoparticle Against Carbapenem-Resistant Acinetobacter baumannii
|
|---|---|
| Published in |
Frontiers in Microbiology, June 2018
|
| DOI | 10.3389/fmicb.2018.01218 |
| Pubmed ID | |
| Authors |
Vishvanath Tiwari, Neha Mishra, Keval Gadani, P. S. Solanki, N. A. Shah, Monalisa Tiwari |
| Abstract |
Acinetobacter baumannii is a multi-drug resistant opportunistic pathogen, which causes respiratory and urinary tract infections. Its prevalence increases gradually in the clinical setup. Carbapenems (beta-lactam) are most effective antibiotics till now against A. baumannii, but the development of resistance against it may lead to high mortality. Therefore, it is of utmost importance to develop an alternative drug against A. baumannii. In the present study, we have synthesized ZnO nanoparticle (ZnO-NP) and characterized by X-ray diffraction, Fourier transform infrared (FTIR) spectroscopy and UV-Visible spectroscopy. Prepared ZnO-NPs have the size of 30 nm and have different characteristics of ZnO-NPs. Growth kinetics and disk diffusion assay showed that ZnO-NP demonstrated good antibacterial activity against carbapenem resistant A. baumannii. We have also investigated the mechanism of action of ZnO-NPs on the carbapenem resistant strain of A. baumannii. The proposed mechanism of action of ZnO involves the production of reactive oxygen species, which elevates membrane lipid peroxidation that causes membrane leakage of reducing sugars, DNA, proteins, and reduces cell viability. These results demonstrate that ZnO-NP could be developed as alternative therapeutics against A. baumannii. |
X Demographics
The data shown below were collected from the profiles of 73 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 4 | 5% |
| Argentina | 3 | 4% |
| Italy | 2 | 3% |
| Nigeria | 2 | 3% |
| Brazil | 2 | 3% |
| Costa Rica | 1 | 1% |
| Venezuela, Bolivarian Republic of | 1 | 1% |
| Namibia | 1 | 1% |
| United States | 1 | 1% |
| Other | 11 | 15% |
| Unknown | 45 | 62% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 59 | 81% |
| Scientists | 11 | 15% |
| Science communicators (journalists, bloggers, editors) | 2 | 3% |
| Practitioners (doctors, other healthcare professionals) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 382 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 382 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 59 | 15% |
| Student > Master | 39 | 10% |
| Researcher | 38 | 10% |
| Student > Bachelor | 25 | 7% |
| Student > Postgraduate | 22 | 6% |
| Other | 63 | 16% |
| Unknown | 136 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 37 | 10% |
| Chemistry | 29 | 8% |
| Materials Science | 27 | 7% |
| Agricultural and Biological Sciences | 27 | 7% |
| Medicine and Dentistry | 17 | 4% |
| Other | 88 | 23% |
| Unknown | 157 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 50. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2020.
All research outputs
#887,598
of 26,194,269 outputs
Outputs from Frontiers in Microbiology
#483
of 30,124 outputs
Outputs of similar age
#18,743
of 345,406 outputs
Outputs of similar age from Frontiers in Microbiology
#13
of 681 outputs
Altmetric has tracked 26,194,269 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 30,124 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,406 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 681 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.