Title |
The Role of Lipoproteins in Mycoplasma-Mediated Immunomodulation
|
---|---|
Published in |
Frontiers in Microbiology, July 2018
|
DOI | 10.3389/fmicb.2018.01682 |
Pubmed ID | |
Authors |
Alexei Christodoulides, Neha Gupta, Vahe Yacoubian, Neil Maithel, Jordan Parker, Theodoros Kelesidis |
Abstract |
Mycoplasma infections, such as walking pneumonia or pelvic inflammatory diseases, are a major threat to public health. Despite their relatively small physical and genomic size, mycoplasmas are known to elicit strong host immune responses, generally inflammatory, while also being able to evade the immune system. The mycoplasma membrane is composed of approximately two-thirds protein and one-third lipid and contains several lipoproteins that are known to regulate host immune responses. Herein, the immunomodulatory effects of mycoplasma lipoproteins are reviewed. A better understanding of the immunomodulatory effects, both activating and evasive, of Mycoplasma surface lipoproteins will contribute to understanding mechanisms potentially relevant to mycoplasma disease vaccine development and treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 15% |
Student > Bachelor | 5 | 13% |
Student > Doctoral Student | 5 | 13% |
Student > Master | 5 | 13% |
Student > Ph. D. Student | 2 | 5% |
Other | 4 | 10% |
Unknown | 13 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 23% |
Agricultural and Biological Sciences | 7 | 18% |
Immunology and Microbiology | 3 | 8% |
Veterinary Science and Veterinary Medicine | 2 | 5% |
Medicine and Dentistry | 2 | 5% |
Other | 1 | 3% |
Unknown | 16 | 40% |