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Utilization of Host-Derived Glycans by Intestinal Lactobacillus and Bifidobacterium Species

Overview of attention for article published in Frontiers in Microbiology, August 2018
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  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

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Title
Utilization of Host-Derived Glycans by Intestinal Lactobacillus and Bifidobacterium Species
Published in
Frontiers in Microbiology, August 2018
DOI 10.3389/fmicb.2018.01917
Pubmed ID
Authors

Manuel Zúñiga, Vicente Monedero, María J. Yebra

Abstract

Members of the genus Lactobacillus are commonly found at the gastrointestinal tract and other mucosal surfaces of humans. This genus includes various species with a great number of potentially probiotic bacteria. Other often-used probiotic species belong to Bifidobacterium, a genus almost exclusively associated with the gut. As probiotics must survive and be metabolically active at their target sites, namely host mucosal surfaces, consumption of host-produced glycans is a key factor for their survival and activity. The ability to metabolize glycans such as human milk oligosaccharides (HMOs), glycosaminoglycans and the glycan moieties of glycoproteins and glycolipids found at the mucosal surfaces grants a competitive advantage to lactobacilli and bifidobacteria. The analyses of the great number of sequenced genomes from these bacteria have revealed that many of them encode a wide assortment of genes involved in the metabolism and transport of carbohydrates, including several glycoside hydrolases required for metabolizing the carbohydrate moieties of mucins and HMOs. Here, the current knowledge on the genetic mechanisms, known catabolic pathways and biochemical properties of enzymes involved in the utilization of host-produced glycans by lactobacilli and bifidobacteria will be summarized.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 141 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 17%
Student > Master 21 15%
Student > Ph. D. Student 20 14%
Student > Bachelor 11 8%
Student > Doctoral Student 7 5%
Other 17 12%
Unknown 41 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 33 23%
Agricultural and Biological Sciences 26 18%
Immunology and Microbiology 19 13%
Chemistry 4 3%
Engineering 4 3%
Other 13 9%
Unknown 42 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2019.
All research outputs
#7,391,755
of 26,151,587 outputs
Outputs from Frontiers in Microbiology
#7,004
of 30,118 outputs
Outputs of similar age
#116,477
of 345,068 outputs
Outputs of similar age from Frontiers in Microbiology
#274
of 741 outputs
Altmetric has tracked 26,151,587 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 30,118 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,068 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 741 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.