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Regulation of Apoptosis During Porcine Circovirus Type 2 Infection

Overview of attention for article published in Frontiers in Microbiology, September 2018
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Title
Regulation of Apoptosis During Porcine Circovirus Type 2 Infection
Published in
Frontiers in Microbiology, September 2018
DOI 10.3389/fmicb.2018.02086
Pubmed ID
Authors

Yuhong Pan, Pengfei Li, Renyong Jia, Mingshu Wang, Zhongqiong Yin, Anchun Cheng

Abstract

Apoptosis, an indispensable innate immune mechanism, regulates cellular homeostasis by removing unnecessary or damaged cells. It contains three signaling pathways: the mitochondria-mediated pathway, the death receptor pathway and the endoplasmic reticulum pathway. The importance of apoptosis in host defenses is stressed by the observation that multiple viruses have evolved various strategies to inhibit apoptosis, thereby blunting the host immune responses and promoting viral propagation. Porcine Circovirus type 2 (PCV2) utilizes various strategies to induce or inhibit programmed cell death. In this article, we review the latest research progress of the apoptosis mechanisms during infection with PCV2, including several proteins of PCV2 regulate apoptosis via interacting with host proteins and multiple signaling pathways involved in PCV2-induced apoptosis, which provides scientific basis for the pathogenesis and prevention of PCV2.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 25%
Researcher 5 25%
Student > Postgraduate 4 20%
Student > Bachelor 3 15%
Student > Ph. D. Student 2 10%
Other 0 0%
Unknown 1 5%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 8 40%
Biochemistry, Genetics and Molecular Biology 5 25%
Agricultural and Biological Sciences 4 20%
Engineering 1 5%
Unknown 2 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2020.
All research outputs
#18,649,666
of 23,103,903 outputs
Outputs from Frontiers in Microbiology
#19,683
of 25,289 outputs
Outputs of similar age
#257,497
of 335,391 outputs
Outputs of similar age from Frontiers in Microbiology
#544
of 692 outputs
Altmetric has tracked 23,103,903 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,289 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,391 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 692 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.