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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Very Preterm Children Gut Microbiota Comparison at the Neonatal Period of 1 Month and 3.5 Years of Life
|
|---|---|
| Published in |
Frontiers in Microbiology, July 2022
|
| DOI | 10.3389/fmicb.2022.919317 |
| Pubmed ID | |
| Authors |
Gaël Toubon, Marie-José Butel, Jean-Christophe Rozé, Patricia Lepage, Johanne Delannoy, Pierre-Yves Ancel, Marie-Aline Charles, Julio Aires, for the EPIFLORE Study Group, Clotilde Rousseau, Joel Dore, Ziad Al Nabhani, Karine Le Roux, Celine Monot, Laetitia MartinMarchand, Melanie Durox, Alexandre Lapillonne, Jean-Charles Picaud, Farid Boudred, Delphine Mitanchez, Valerie Biran, Laurent Storme, Olivier Claris, Gilles Cambonie, Cyril Flamant, Anne Sauret, Odile Dicky, Geraldine Favrais, Jean-Michel Hascoet, Geraldine Gascoin, Gerard Thiriez, Luc Desfrere, Xavier Durrmeyer, Clement Chollat |
| Abstract |
Prematurity is a risk factor for dysbiosis of the gut microbiota due to particular birth conditions and frequent prolonged hospitalization of neonates. Although gut microbiota colonization after birth and its establishment during the hospitalization period have been studied in preterm infants, data on gut microbiota following discharge, particularly during early childhood, are scarce. The present study investigated the relationship between gut microbiota at 1 month after birth (hospitalization period) and 3.5 years of age in 159 preterm children belonging to the French EPIFLORE prospective observational cohort study. Analysis using bacterial 16S rRNA gene sequencing showed that the gut microbiota of preterm neonates at 1 month was highly variable and characterized by six distinct enterotypes. In contrast, the gut microbiota of the same children at 3.5 years of age showed less variability, with only two discrete enterotypes. An absence of association between enterotypes at 1 month and 3.5 years of age was observed. While the alpha diversity of gut microbiota significantly increased between 1 month and 3.5 years of age, for both alpha and beta diversities, there was no correlation between the 1-month and 3.5-years time points. Comparison at 3.5 years between children born either preterm (n = 159) or full-term (n = 200) showed no differences in terms of enterotypes, but preterm children harbored a lower Shannon diversity index and a different overall composition of microbiota than full-term children. This study suggests that the characteristics of the early gut microbiota of preterm children are not predictive of the microbial community composition at 3.5 years of age. However, the impact of gestational age is still noticeable on the gut microbiota up to 3.5 years of age. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 15 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 33% |
| Student > Doctoral Student | 2 | 13% |
| Lecturer | 1 | 7% |
| Professor | 1 | 7% |
| Student > Master | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 5 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 13% |
| Medicine and Dentistry | 2 | 13% |
| Immunology and Microbiology | 2 | 13% |
| Philosophy | 1 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
| Other | 2 | 13% |
| Unknown | 5 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2022.
All research outputs
#17,340,991
of 25,443,857 outputs
Outputs from Frontiers in Microbiology
#18,114
of 29,374 outputs
Outputs of similar age
#255,490
of 434,192 outputs
Outputs of similar age from Frontiers in Microbiology
#744
of 1,268 outputs
Altmetric has tracked 25,443,857 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 29,374 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 434,192 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,268 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.