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X Demographics
Mendeley readers
Attention Score in Context
| Title |
How can EPR spectroscopy help to unravel molecular mechanisms of flavin-dependent photoreceptors?
|
|---|---|
| Published in |
Frontiers in Molecular Biosciences, September 2015
|
| DOI | 10.3389/fmolb.2015.00049 |
| Pubmed ID | |
| Authors |
Daniel Nohr, Ryan Rodriguez, Stefan Weber, Erik Schleicher |
| Abstract |
Electron paramagnetic resonance (EPR) spectroscopy is a well-established spectroscopic method for the examination of paramagnetic molecules. Proteins can contain paramagnetic moieties in form of stable cofactors, transiently formed intermediates, or spin labels artificially introduced to cysteine sites. The focus of this review is to evaluate potential scopes of application of EPR to the emerging field of optogenetics. The main objective for EPR spectroscopy in this context is to unravel the complex mechanisms of light-active proteins, from their primary photoreaction to downstream signal transduction. An overview of recent results from the family of flavin-containing, blue-light dependent photoreceptors is given. In detail, mechanistic similarities and differences are condensed from the three classes of flavoproteins, the cryptochromes, LOV (Light-oxygen-voltage), and BLUF (blue-light using FAD) domains. Additionally, a concept that includes spin-labeled proteins and examination using modern pulsed EPR is introduced, which allows for a precise mapping of light-induced conformational changes. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Israel | 1 | 2% |
| Unknown | 58 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 31% |
| Researcher | 10 | 17% |
| Student > Master | 6 | 10% |
| Student > Bachelor | 5 | 8% |
| Student > Doctoral Student | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 13 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 22 | 37% |
| Biochemistry, Genetics and Molecular Biology | 8 | 14% |
| Agricultural and Biological Sciences | 7 | 12% |
| Physics and Astronomy | 3 | 5% |
| Engineering | 2 | 3% |
| Other | 3 | 5% |
| Unknown | 14 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2015.
All research outputs
#14,696,666
of 22,826,360 outputs
Outputs from Frontiers in Molecular Biosciences
#1,267
of 3,776 outputs
Outputs of similar age
#145,537
of 266,863 outputs
Outputs of similar age from Frontiers in Molecular Biosciences
#7
of 16 outputs
Altmetric has tracked 22,826,360 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,776 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,863 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.