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A delicate balance: Iron metabolism and diseases of the brain

Overview of attention for article published in Frontiers in Aging Neuroscience, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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11 X users
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1 Facebook page

Citations

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337 Dimensions

Readers on

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382 Mendeley
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Title
A delicate balance: Iron metabolism and diseases of the brain
Published in
Frontiers in Aging Neuroscience, January 2013
DOI 10.3389/fnagi.2013.00034
Pubmed ID
Authors

Dominic Hare, Scott Ayton, Ashley Bush, Peng Lei

Abstract

Iron is the most abundant transition metal within the brain, and is vital for a number of cellular processes including neurotransmitter synthesis, myelination of neurons, and mitochondrial function. Redox cycling between ferrous and ferric iron is utilized in biology for various electron transfer reactions essential to life, yet this same chemistry mediates deleterious reactions with oxygen that induce oxidative stress. Consequently, there is a precise and tightly controlled mechanism to regulate iron in the brain. When iron is dysregulated, both conditions of iron overload and iron deficiencies are harmful to the brain. This review focuses on how iron metabolism is maintained in the brain, and how an alteration to iron and iron metabolism adversely affects neurological function.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 382 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hungary 1 <1%
United States 1 <1%
Estonia 1 <1%
Unknown 379 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 71 19%
Researcher 52 14%
Student > Bachelor 45 12%
Student > Master 40 10%
Student > Doctoral Student 20 5%
Other 57 15%
Unknown 97 25%
Readers by discipline Count As %
Medicine and Dentistry 64 17%
Agricultural and Biological Sciences 57 15%
Neuroscience 43 11%
Biochemistry, Genetics and Molecular Biology 35 9%
Chemistry 24 6%
Other 52 14%
Unknown 107 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2023.
All research outputs
#5,079,222
of 25,299,129 outputs
Outputs from Frontiers in Aging Neuroscience
#2,640
of 5,464 outputs
Outputs of similar age
#50,501
of 293,554 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#23
of 77 outputs
Altmetric has tracked 25,299,129 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,464 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.5. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 293,554 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.