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X Demographics
Mendeley readers
Attention Score in Context
| Title |
DNA methylation, a hand behind neurodegenerative diseases
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, January 2013
|
| DOI | 10.3389/fnagi.2013.00085 |
| Pubmed ID | |
| Authors |
Haoyang Lu, Xinzhou Liu, Yulin Deng, Hong Qing |
| Abstract |
Epigenetic alterations represent a sort of functional modifications related to the genome that are not responsible for changes in the nucleotide sequence. DNA methylation is one of such epigenetic modifications that have been studied intensively for the past several decades. The transfer of a methyl group to the 5 position of a cytosine is the key feature of DNA methylation. A simple change as such can be caused by a variety of factors, which can be the cause of many serious diseases including several neurodegenerative diseases. In this review, we have reviewed and summarized recent progress regarding DNA methylation in four major neurodegenerative diseases: Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS). The studies of these four major neurodegenerative diseases conclude the strong suggestion of the important role DNA methylation plays in these diseases. However, each of these diseases has not yet been understood completely as details in some areas remain unclear, and will be investigated in future studies. We hope this review can provide new insights into the understanding of neurodegenerative diseases from the epigenetic perspective. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 259 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 3 | 1% |
| United States | 2 | <1% |
| Brazil | 1 | <1% |
| Portugal | 1 | <1% |
| United Kingdom | 1 | <1% |
| Czechia | 1 | <1% |
| Unknown | 250 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 61 | 24% |
| Researcher | 38 | 15% |
| Student > Master | 38 | 15% |
| Student > Bachelor | 35 | 14% |
| Student > Doctoral Student | 10 | 4% |
| Other | 33 | 13% |
| Unknown | 44 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 72 | 28% |
| Biochemistry, Genetics and Molecular Biology | 48 | 19% |
| Medicine and Dentistry | 33 | 13% |
| Neuroscience | 23 | 9% |
| Chemistry | 6 | 2% |
| Other | 23 | 9% |
| Unknown | 54 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2020.
All research outputs
#5,406,469
of 22,757,541 outputs
Outputs from Frontiers in Aging Neuroscience
#2,232
of 4,747 outputs
Outputs of similar age
#56,481
of 280,892 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#23
of 77 outputs
Altmetric has tracked 22,757,541 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,747 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,892 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.