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The Fornix in Mild Cognitive Impairment and Alzheimer’s Disease

Overview of attention for article published in Frontiers in Aging Neuroscience, January 2015
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Title
The Fornix in Mild Cognitive Impairment and Alzheimer’s Disease
Published in
Frontiers in Aging Neuroscience, January 2015
DOI 10.3389/fnagi.2015.00001
Pubmed ID
Authors

Milap A. Nowrangi, Paul B. Rosenberg

Abstract

The fornix is an integral white matter bundle located in the medial diencephalon and is part of the limbic structures. It serves a vital role in memory functions and as such has become the subject of recent research emphasis in Alzheimer's disease (AD) and mild cognitive impairment (MCI). As the characteristic pathological processes of AD progress, structural and functional changes to the medial temporal lobes and other regions become evident years before clinical symptoms are present. Though gray matter atrophy has been the most studied, degradation of white matter structures especially the fornix may precede these and has become detectable with use of diffusion tensor imaging (DTI) and other complimentary imaging techniques. Recent research utilizing DTI measurement of the fornix has shown good discriminability of diagnostic groups, particularly early and preclinical, as well as predictive power for incident MCI and AD. Stimulating and modulating fornix function by the way of DBS has been an exciting new area as pharmacological therapeutics has been slow to develop.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 3%
Mexico 1 1%
United States 1 1%
Denmark 1 1%
Unknown 93 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 20%
Researcher 17 17%
Student > Master 13 13%
Student > Postgraduate 9 9%
Student > Doctoral Student 9 9%
Other 17 17%
Unknown 14 14%
Readers by discipline Count As %
Neuroscience 29 29%
Psychology 12 12%
Medicine and Dentistry 11 11%
Agricultural and Biological Sciences 7 7%
Engineering 6 6%
Other 14 14%
Unknown 20 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2015.
All research outputs
#15,321,186
of 22,787,797 outputs
Outputs from Frontiers in Aging Neuroscience
#3,591
of 4,764 outputs
Outputs of similar age
#209,114
of 351,758 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#25
of 33 outputs
Altmetric has tracked 22,787,797 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,764 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,758 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.