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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson’s Disease
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, March 2016
|
| DOI | 10.3389/fnagi.2016.00065 |
| Pubmed ID | |
| Authors |
Juhyun Song, Jongpil Kim |
| Abstract |
The rates of metabolic diseases, such as type 2 diabetes mellitus (T2DM), obesity, and cardiovascular disease (CVD), markedly increase with age. In recent years, studies have reported an association between metabolic changes and various pathophysiological mechanisms in the central nervous system (CNS) in patients with metabolic diseases. Oxidative stress and hyperglycemia in metabolic diseases lead to adverse neurophysiological phenomena, including neuronal loss, synaptic dysfunction, and improper insulin signaling, resulting in Parkinson's disease (PD). In addition, several lines of evidence suggest that alterations of CNS environments by metabolic changes influence the dopamine neuronal loss, eventually affecting the pathogenesis of PD. Thus, we reviewed recent findings relating to degeneration of dopaminergic neurons during metabolic diseases. We highlight the fact that using a metabolic approach to manipulate degeneration of dopaminergic neurons can serve as a therapeutic strategy to attenuate pathology of PD. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 29% |
| Unknown | 5 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Scientists | 3 | 43% |
Mendeley readers
The data shown below were compiled from readership statistics for 167 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 167 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 19% |
| Student > Master | 26 | 16% |
| Researcher | 23 | 14% |
| Student > Bachelor | 22 | 13% |
| Student > Doctoral Student | 8 | 5% |
| Other | 19 | 11% |
| Unknown | 38 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 33 | 20% |
| Biochemistry, Genetics and Molecular Biology | 23 | 14% |
| Medicine and Dentistry | 22 | 13% |
| Agricultural and Biological Sciences | 19 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 4% |
| Other | 18 | 11% |
| Unknown | 45 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2018.
All research outputs
#6,971,469
of 22,858,915 outputs
Outputs from Frontiers in Aging Neuroscience
#2,545
of 4,803 outputs
Outputs of similar age
#99,170
of 300,631 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#41
of 80 outputs
Altmetric has tracked 22,858,915 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 4,803 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,631 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.