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An Activation Likelihood Estimation Meta-Analysis Study of Simple Motor Movements in Older and Young Adults

Overview of attention for article published in Frontiers in Aging Neuroscience, October 2016
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Title
An Activation Likelihood Estimation Meta-Analysis Study of Simple Motor Movements in Older and Young Adults
Published in
Frontiers in Aging Neuroscience, October 2016
DOI 10.3389/fnagi.2016.00238
Pubmed ID
Authors

Ted K. Turesky, Peter E. Turkeltaub, Guinevere F. Eden

Abstract

The functional neuroanatomy of finger movements has been characterized with neuroimaging in young adults. However, less is known about the aging motor system. Several studies have contrasted movement-related activity in older versus young adults, but there is inconsistency among their findings. To address this, we conducted an activation likelihood estimation (ALE) meta-analysis on within-group data from older adults and young adults performing regularly paced right-hand finger movement tasks in response to external stimuli. We hypothesized that older adults would show a greater likelihood of activation in right cortical motor areas (i.e., ipsilateral to the side of movement) compared to young adults. ALE maps were examined for conjunction and between-group differences. Older adults showed overlapping likelihoods of activation with young adults in left primary sensorimotor cortex (SM1), bilateral supplementary motor area, bilateral insula, left thalamus, and right anterior cerebellum. Their ALE map differed from that of the young adults in right SM1 (extending into dorsal premotor cortex), right supramarginal gyrus, medial premotor cortex, and right posterior cerebellum. The finding that older adults uniquely use ipsilateral regions for right-hand finger movements and show age-dependent modulations in regions recruited by both age groups provides a foundation by which to understand age-related motor decline and motor disorders.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 16%
Researcher 8 16%
Student > Bachelor 8 16%
Student > Master 5 10%
Student > Doctoral Student 3 6%
Other 7 14%
Unknown 10 20%
Readers by discipline Count As %
Neuroscience 15 31%
Psychology 7 14%
Sports and Recreations 3 6%
Nursing and Health Professions 2 4%
Philosophy 1 2%
Other 7 14%
Unknown 14 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2016.
All research outputs
#17,820,151
of 22,893,031 outputs
Outputs from Frontiers in Aging Neuroscience
#3,819
of 4,823 outputs
Outputs of similar age
#225,329
of 315,552 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#53
of 72 outputs
Altmetric has tracked 22,893,031 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
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