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Neurodegeneration and the Circadian Clock

Overview of attention for article published in Frontiers in Aging Neuroscience, May 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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24 X users
facebook
2 Facebook pages
googleplus
1 Google+ user

Citations

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111 Dimensions

Readers on

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201 Mendeley
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Title
Neurodegeneration and the Circadian Clock
Published in
Frontiers in Aging Neuroscience, May 2017
DOI 10.3389/fnagi.2017.00170
Pubmed ID
Authors

Suzanne Hood, Shimon Amir

Abstract

Despite varied etiologies and symptoms, several neurodegenerative diseases-specifically, Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HDs)-share the common feature of abnormal circadian rhythms, such as those in behavior (e.g., disrupted sleep/wake cycles), physiological processes (e.g., diminished hormone release) and biochemical activities (e.g., antioxidant production). Circadian disturbances are among the earliest symptoms of these diseases, and the molecular mechanisms of the circadian system are suspected to play a pivotal, and possibly causal, role in their natural histories. Here, we review the common circadian abnormalities observed in ADs, PDs and HDs, and summarize the evidence that the molecular circadian clockwork directly influences the course of these disease states. On the basis of this research, we explore several circadian-oriented interventions proposed as treatments for these neurological disorders.

X Demographics

X Demographics

The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Germany 1 <1%
Unknown 199 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 31 15%
Student > Ph. D. Student 26 13%
Student > Master 21 10%
Researcher 18 9%
Student > Doctoral Student 13 6%
Other 32 16%
Unknown 60 30%
Readers by discipline Count As %
Neuroscience 32 16%
Biochemistry, Genetics and Molecular Biology 28 14%
Medicine and Dentistry 27 13%
Agricultural and Biological Sciences 18 9%
Psychology 7 3%
Other 22 11%
Unknown 67 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2022.
All research outputs
#2,537,126
of 26,311,549 outputs
Outputs from Frontiers in Aging Neuroscience
#813
of 5,672 outputs
Outputs of similar age
#44,799
of 335,053 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#34
of 120 outputs
Altmetric has tracked 26,311,549 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,672 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,053 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 120 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.