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In vivo Brainstem Imaging in Alzheimer’s Disease: Potential for Biomarker Development

Overview of attention for article published in Frontiers in Aging Neuroscience, September 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
7 news outlets
twitter
5 X users

Citations

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13 Dimensions

Readers on

mendeley
42 Mendeley
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Title
In vivo Brainstem Imaging in Alzheimer’s Disease: Potential for Biomarker Development
Published in
Frontiers in Aging Neuroscience, September 2018
DOI 10.3389/fnagi.2018.00266
Pubmed ID
Authors

David J. Braun, Linda J. Van Eldik

Abstract

The dearth of effective treatments for Alzheimer's disease (AD) is one of the largest public health issues worldwide, costing hundreds of billions of dollars per year. From a therapeutic standpoint, research efforts to date have met with strikingly little clinical success. One major issue is that trials begin after substantial pathological change has occurred, and it is increasingly clear that the most effective treatment regimens will need to be administered earlier in the disease process. In order to identify individuals within the long preclinical phase of AD who are likely to progress to dementia, improvements are required in biomarker development. One potential area of research that might prove fruitful in this regard is the in vivo detection of brainstem pathology. The brainstem is known to undergo pathological changes very early and progressively in AD. With an updated and harmonized AD research framework, and emerging advances in neuroimaging technology, the potential to leverage knowledge of brainstem pathology into biomarkers for AD will be discussed.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 21%
Researcher 8 19%
Student > Master 5 12%
Other 4 10%
Student > Doctoral Student 2 5%
Other 5 12%
Unknown 9 21%
Readers by discipline Count As %
Neuroscience 9 21%
Engineering 5 12%
Medicine and Dentistry 5 12%
Psychology 4 10%
Computer Science 2 5%
Other 5 12%
Unknown 12 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 56. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2018.
All research outputs
#656,617
of 23,103,436 outputs
Outputs from Frontiers in Aging Neuroscience
#128
of 4,872 outputs
Outputs of similar age
#15,637
of 337,560 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#5
of 107 outputs
Altmetric has tracked 23,103,436 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,872 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,560 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 107 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.