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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Exploring the Pharmacological Potential of Metformin for Neurodegenerative Diseases
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, April 2022
|
| DOI | 10.3389/fnagi.2022.838173 |
| Pubmed ID | |
| Authors |
Ming-Rui Du, Quan-You Gao, Chen-Lin Liu, Lin-Ya Bai, Tian Li, Fei-Long Wei |
| Abstract |
Metformin, one of the first-line of hypoglycemic drugs, has cardioprotective, anti-inflammatory and anticancer activities, in addition to its proven hypoglycemic effects. Furthermore, the preventive and therapeutic potential of metformin for neurodegenerative diseases has become a topic of concern. Increasing research suggests that metformin can prevent the progression of neurodegenerative diseases. In recent years, many studies have investigated the neuroprotective effect of metformin in the treatment of neurodegenerative diseases. It has been revealed that metformin can play a neuroprotective role by regulating energy metabolism, oxidative stress, inflammatory response and protein deposition of cells, and avoiding neuronal dysfunction and neuronal death. On the contrary, some have hypothesized that metformin has a two-sided effect which may accelerate the progression of neurodegenerative diseases. In this review, the results of animal experiments and clinical studies are reviewed to discuss the application prospects of metformin in neurodegenerative diseases. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 13% |
| Student > Bachelor | 5 | 11% |
| Student > Master | 3 | 7% |
| Researcher | 2 | 4% |
| Lecturer | 1 | 2% |
| Other | 5 | 11% |
| Unknown | 23 | 51% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 11% |
| Biochemistry, Genetics and Molecular Biology | 4 | 9% |
| Medicine and Dentistry | 4 | 9% |
| Chemistry | 2 | 4% |
| Computer Science | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 27 | 60% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2023.
All research outputs
#3,132,956
of 23,392,375 outputs
Outputs from Frontiers in Aging Neuroscience
#1,442
of 4,941 outputs
Outputs of similar age
#68,896
of 443,535 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#70
of 331 outputs
Altmetric has tracked 23,392,375 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,941 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 443,535 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 331 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.