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From a meso- to micro-scale connectome: array tomography and mGRASP

Overview of attention for article published in Frontiers in Neuroanatomy, June 2015
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3 X users
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1 Facebook page

Citations

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15 Dimensions

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118 Mendeley
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Title
From a meso- to micro-scale connectome: array tomography and mGRASP
Published in
Frontiers in Neuroanatomy, June 2015
DOI 10.3389/fnana.2015.00078
Pubmed ID
Authors

Jong-Cheol Rah, Linqing Feng, Shaul Druckmann, Hojin Lee, Jinhyun Kim

Abstract

Mapping mammalian synaptic connectivity has long been an important goal of neuroscience because knowing how neurons and brain areas are connected underpins an understanding of brain function. Meeting this goal requires advanced techniques with single synapse resolution and large-scale capacity, especially at multiple scales tethering the meso- and micro-scale connectome. Among several advanced LM-based connectome technologies, Array Tomography (AT) and mammalian GFP-Reconstitution Across Synaptic Partners (mGRASP) can provide relatively high-throughput mapping synaptic connectivity at multiple scales. AT- and mGRASP-assisted circuit mapping (ATing and mGRASPing), combined with techniques such as retrograde virus, brain clearing techniques, and activity indicators will help unlock the secrets of complex neural circuits. Here, we discuss these useful new tools to enable mapping of brain circuits at multiple scales, some functional implications of spatial synaptic distribution, and future challenges and directions of these endeavors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 <1%
Switzerland 1 <1%
Unknown 116 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 26 22%
Student > Ph. D. Student 21 18%
Student > Bachelor 11 9%
Student > Master 10 8%
Professor > Associate Professor 9 8%
Other 23 19%
Unknown 18 15%
Readers by discipline Count As %
Neuroscience 42 36%
Agricultural and Biological Sciences 27 23%
Medicine and Dentistry 6 5%
Engineering 6 5%
Biochemistry, Genetics and Molecular Biology 5 4%
Other 11 9%
Unknown 21 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2015.
All research outputs
#13,436,543
of 22,807,037 outputs
Outputs from Frontiers in Neuroanatomy
#574
of 1,159 outputs
Outputs of similar age
#126,943
of 267,104 outputs
Outputs of similar age from Frontiers in Neuroanatomy
#23
of 41 outputs
Altmetric has tracked 22,807,037 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,159 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,104 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.