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Mendeley readers
Attention Score in Context
| Title |
The serotonin receptor 7 and the structural plasticity of brain circuits
|
|---|---|
| Published in |
Frontiers in Behavioral Neuroscience, September 2014
|
| DOI | 10.3389/fnbeh.2014.00318 |
| Pubmed ID | |
| Authors |
Floriana Volpicelli, Luisa Speranza, Umberto di Porzio, Marianna Crispino, Carla Perrone-Capano |
| Abstract |
Serotonin (5-hydroxytryptamine, 5-HT) modulates numerous physiological processes in the nervous system. Together with its function as neurotransmitter, 5-HT regulates neurite outgrowth, dendritic spine shape and density, growth cone motility and synapse formation during development. In the mammalian brain 5-HT innervation is virtually ubiquitous and the diversity and specificity of its signaling and function arise from at least 20 different receptors, grouped in 7 classes. Here we will focus on the role 5-HT7 receptor (5-HT7R) in the correct establishment of neuronal cytoarchitecture during development, as also suggested by its involvement in several neurodevelopmental disorders. The emerging picture shows that this receptor is a key player contributing not only to shape brain networks during development but also to remodel neuronal wiring in the mature brain, thus controlling cognitive and emotional responses. The activation of 5-HT7R might be one of the mechanisms underlying the ability of the CNS to respond to different stimuli by modulation of its circuit configuration. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 75 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 16% |
| Student > Master | 11 | 14% |
| Student > Bachelor | 11 | 14% |
| Researcher | 9 | 12% |
| Student > Doctoral Student | 5 | 6% |
| Other | 13 | 17% |
| Unknown | 16 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 20 | 26% |
| Medicine and Dentistry | 10 | 13% |
| Agricultural and Biological Sciences | 10 | 13% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Other | 9 | 12% |
| Unknown | 20 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2014.
All research outputs
#20,239,689
of 22,766,595 outputs
Outputs from Frontiers in Behavioral Neuroscience
#2,821
of 3,160 outputs
Outputs of similar age
#203,643
of 243,377 outputs
Outputs of similar age from Frontiers in Behavioral Neuroscience
#75
of 86 outputs
Altmetric has tracked 22,766,595 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,160 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,377 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.