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Binge-Like Sucrose Self-Administration Experience Inhibits Cocaine and Sucrose Seeking Behavior in Offspring

Overview of attention for article published in Frontiers in Behavioral Neuroscience, September 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

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19 X users

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Title
Binge-Like Sucrose Self-Administration Experience Inhibits Cocaine and Sucrose Seeking Behavior in Offspring
Published in
Frontiers in Behavioral Neuroscience, September 2017
DOI 10.3389/fnbeh.2017.00184
Pubmed ID
Authors

Qiumin Le, Yanqing Li, Weiqing Hou, Biao Yan, Xiangchen Yu, Haikun Song, Feifei Wang, Lan Ma

Abstract

Recent studies show that emotional and environmental stimuli promote epigenetic inheritance and influence behavioral development in the subsequent generations. Caloric mal- and under-nutrition has been shown to cause metabolic disturbances in the subsequent generation, but the incentive properties of paternal binge-like eating in offspring is still unknown. Here we show that paternal sucrose self-administration experience could induce inter-generational decrease in both sucrose and cocaine-seeking behavior, and sucrose responding in F1 rats, but not F2, correlated with the performance of F0 rats in sucrose self-administration. Higher anxiety level and decreased cocaine sensitivity were observed in Sucrose F1 compared with Control F1, possibly contributing to the desensitization phenotype in cocaine and sucrose self-administration. Our study revealed that paternal binge-like sucrose consumption causes decrease in reward seeking and induces anxiety-like behavior in the F1 offspring.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 17%
Student > Master 4 11%
Student > Bachelor 4 11%
Researcher 3 9%
Student > Doctoral Student 2 6%
Other 1 3%
Unknown 15 43%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 14%
Agricultural and Biological Sciences 4 11%
Psychology 4 11%
Neuroscience 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Other 4 11%
Unknown 13 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2017.
All research outputs
#3,145,954
of 26,117,612 outputs
Outputs from Frontiers in Behavioral Neuroscience
#534
of 3,492 outputs
Outputs of similar age
#54,626
of 332,597 outputs
Outputs of similar age from Frontiers in Behavioral Neuroscience
#14
of 74 outputs
Altmetric has tracked 26,117,612 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,492 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,597 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.