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The Action Representation Elicited by Different Types of Drug-Related Cues in Heroin-Abstinent Individuals

Overview of attention for article published in Frontiers in Behavioral Neuroscience, July 2018
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Title
The Action Representation Elicited by Different Types of Drug-Related Cues in Heroin-Abstinent Individuals
Published in
Frontiers in Behavioral Neuroscience, July 2018
DOI 10.3389/fnbeh.2018.00123
Pubmed ID
Authors

Hong Zeng, Dequan Su, Pengfei Wang, Mengcheng Wang, Sabine Vollstädt-Klein, Qi Chen, Haosheng Ye

Abstract

Drug related cue-induced reactivity plays a significant role in maintaining drug use and relapse in addicted individuals. The activation of Dorsolateral striatum-Sensorimotor system (DLS-SM) has been suggested as an important route through which drug cues may induce automatic drug using behavior. The current study used fMRI to investigate the reactivity of heroin abstinent individuals to different types of cues, to clarify the characteristics of the cues that induce the activation of the sensorimotor area. Forty heroin-dependent abstinent individuals and 29 healthy subjects were recruited to perform the heroin cue-reactivity task during fMRI. The participants' subjective craving and physical signs were evaluated before and after scanning. Whole-brain analysis showed that compared to drug use tool and drug cues, cues related to drug use action were more likely to activate posterior central gyrus, para-hippocampus, supra marginal gyrus, superior parietal lobule (SPL) and inferior parietal lobule (IPL). These areas are involved in motor preparation and output, indicating that the sensorimotor area is also an important neural basis of craving and automatic drug using behavior, and may mediate craving and drug seeking behavior. Our findings thus suggest that cues related to drug using action may induce automatic drug seeking behavior more than cues related only to the drug itself.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 17%
Student > Master 4 11%
Researcher 3 9%
Student > Bachelor 3 9%
Lecturer > Senior Lecturer 2 6%
Other 4 11%
Unknown 13 37%
Readers by discipline Count As %
Psychology 7 20%
Medicine and Dentistry 5 14%
Neuroscience 2 6%
Social Sciences 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 1 3%
Unknown 17 49%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2018.
All research outputs
#17,976,833
of 23,085,832 outputs
Outputs from Frontiers in Behavioral Neuroscience
#2,438
of 3,212 outputs
Outputs of similar age
#236,996
of 327,915 outputs
Outputs of similar age from Frontiers in Behavioral Neuroscience
#68
of 72 outputs
Altmetric has tracked 23,085,832 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,212 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.3. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,915 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.