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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Possible role of glial cells in the relationship between thyroid dysfunction and mental disorders
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, June 2015
|
| DOI | 10.3389/fncel.2015.00194 |
| Pubmed ID | |
| Authors |
Mami Noda |
| Abstract |
It is widely accepted that there is a close relationship between the endocrine system and the central nervous system (CNS). Among hormones closely related to the nervous system, thyroid hormones (THs) are critical for the development and function of the CNS; not only for neuronal cells but also for glial development and differentiation. Any impairment of TH supply to the developing CNS causes severe and irreversible changes in the overall architecture and function of the human brain, leading to various neurological dysfunctions. In the adult brain, impairment of THs, such as hypothyroidism and hyperthyroidism, can cause psychiatric disorders such as schizophrenia, bipolar disorder, anxiety and depression. Although impact of hypothyroidism on synaptic transmission and plasticity is known, its effect on glial cells and related cellular mechanisms remain enigmatic. This mini-review article summarizes how THs are transported into the brain, metabolized in astrocytes and affect microglia and oligodendrocytes, demonstrating an example of glioendocrine system. Neuroglial effects may help to understand physiological and/or pathophysiological functions of THs in the CNS and how hypo- and hyper-thyroidism may cause mental disorders. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 19% |
| Australia | 1 | 6% |
| Netherlands | 1 | 6% |
| Switzerland | 1 | 6% |
| Chile | 1 | 6% |
| Unknown | 9 | 56% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 12 | 75% |
| Practitioners (doctors, other healthcare professionals) | 3 | 19% |
| Scientists | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Switzerland | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 128 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 17% |
| Student > Bachelor | 19 | 14% |
| Student > Master | 14 | 11% |
| Student > Ph. D. Student | 13 | 10% |
| Student > Doctoral Student | 7 | 5% |
| Other | 25 | 19% |
| Unknown | 31 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 23% |
| Agricultural and Biological Sciences | 22 | 17% |
| Biochemistry, Genetics and Molecular Biology | 12 | 9% |
| Neuroscience | 10 | 8% |
| Nursing and Health Professions | 5 | 4% |
| Other | 16 | 12% |
| Unknown | 37 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2023.
All research outputs
#3,697,719
of 26,189,645 outputs
Outputs from Frontiers in Cellular Neuroscience
#761
of 4,776 outputs
Outputs of similar age
#44,584
of 281,742 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#22
of 117 outputs
Altmetric has tracked 26,189,645 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,776 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,742 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.