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The Revolution in Migraine Genetics: From Aching Channels Disorders to a Next-Generation Medicine

Overview of attention for article published in Frontiers in Cellular Neuroscience, June 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

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10 X users
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4 Facebook pages
reddit
1 Redditor

Citations

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20 Dimensions

Readers on

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62 Mendeley
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Title
The Revolution in Migraine Genetics: From Aching Channels Disorders to a Next-Generation Medicine
Published in
Frontiers in Cellular Neuroscience, June 2016
DOI 10.3389/fncel.2016.00156
Pubmed ID
Authors

Simona Pellacani, Federico Sicca, Cherubino Di Lorenzo, Gaetano S. Grieco, Giulia Valvo, Cristina Cereda, Anna Rubegni, Filippo M. Santorelli

Abstract

Channelopathies are a heterogeneous group of neurological disorders resulting from dysfunction of ion channels located in cell membranes and organelles. The clinical scenario is broad and symptoms such as generalized epilepsy (with or without fever), migraine (with or without aura), episodic ataxia and periodic muscle paralysis are some of the best known consequences of gain- or loss-of-function mutations in ion channels. We review the main clinical effects of ion channel mutations associated with a significant impact on migraine headache. Given the increasing and evolving use of genetic analysis in migraine research-greater emphasis is now placed on genetic markers of dysfunctional biological systems-we also show how novel information in rare monogenic forms of migraine might help to clarify the disease mechanisms in the general population of migraineurs. Next-generation sequencing (NGS) and more accurate and precise phenotyping strategies are expected to further increase understanding of migraine pathophysiology and genetics.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 61 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 27%
Student > Master 8 13%
Student > Bachelor 7 11%
Student > Ph. D. Student 5 8%
Student > Doctoral Student 4 6%
Other 12 19%
Unknown 9 15%
Readers by discipline Count As %
Medicine and Dentistry 16 26%
Neuroscience 11 18%
Biochemistry, Genetics and Molecular Biology 4 6%
Agricultural and Biological Sciences 4 6%
Nursing and Health Professions 3 5%
Other 7 11%
Unknown 17 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2020.
All research outputs
#3,903,437
of 22,877,793 outputs
Outputs from Frontiers in Cellular Neuroscience
#804
of 4,256 outputs
Outputs of similar age
#69,638
of 352,763 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#9
of 74 outputs
Altmetric has tracked 22,877,793 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,256 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,763 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.